Argan oil is derived from the kernels of the argan tree that is endemic to Morocco. In that country, argan oil has been used for skin and hair problems for centuries.  In the western world, argan oil is now becoming very popular in cosmetic applications. Art Naturals organic argan oil shampoo also includes a huge list of botanical and herbal products, along with essential oils that will improve the texture of your hair significantly.
“I also reached out to Histogen and Follicum a few weeks ago as well thanking them for all their hard work in bringing a safe and effective treatment to people all over the globe with hairloss issues and expressed how much we all value these companies. I held back from asking about market release as you had suggested. I received a very nice reply from Histogen.”
A diet that is poor or lacking in certain nutrients, particularly iron, protein, and vitamin B, which are essential in the production of keratin, can cause a long telogen phase and a very short anagen stage. On the other hand, excess supply of vitamin A in the body, especially those taken through supplements, can prove to be toxic and can cause a range of adverse body effects including loss of appetite, fatigue and consequently, hair loss.

One hard truth: Hair loss is mostly out of your control. “Baldness comes down to your genes,” says Frederick Joyce, M.D., founder of Rejuvenate! Med Spa and a member of the International Society for Hair Restoration Surgery. “If you have the baldness gene, there are some natural remedies that may make your hair stronger and healthier to slow your hair loss slightly—but they won’t prevent you from going bald. Still, maintaining hair health by eating well and using the right products—combined with medical-grade treatments—can really work all together to help you have a fuller, thicker head of hair.”
Follicular Unit Extraction (FUE). In this method, instead of taking out a whole sample strip, small, individual follicle grafts are cut using a machine and then transplanted. The process is more tedious and more time-consuming, but has been known to have a higher recovery rate and there are no risks of scarring because no cuts and stitches are required.

I’ve just come across the official press release from Organ Technologies (the biotech company which is developing Tsuji’s methods) regarding their recent advancements in hair follicle cloning. It contains the important information which has already been listed on Follicle Thought, though it  also includes many more details. The press release is titled Organ Technologies and RIKEN Launch Preclinical Tests in Hair Follicle Regenerative Medicine. 
The most common form of hair loss is androgenetic alopecia, or, in other words, male or female pattern baldness or hair loss. Androgenetic alopecia is genetic and affects an estimated 50 million men and 30 million women in the United States. Among white women in the U.S., an average of 19% are affected by female pattern hair loss, but that percentage increases with age. The prevalence is nearly doubled in Australia at 32% and much lower in Korea and China at < 6%. As of 2015, no studies had been done on the prevalence of female pattern hair loss in Brazil or Africa.
Some treatments in development hold particular promise for women. Angela Christiano, a hair geneticist and Columbia University professor of dermatology, is hoping to begin clinical trials in a year or two on a procedure in which she dissects hair-follicle stem cells, grows them in the lab until she has several million, then injects them into the scalp, where, a very small study done with a human skin model has shown, they induce new hairs.

Some treatments in development hold particular promise for women. Angela Christiano, a hair geneticist and Columbia University professor of dermatology, is hoping to begin clinical trials in a year or two on a procedure in which she dissects hair-follicle stem cells, grows them in the lab until she has several million, then injects them into the scalp, where, a very small study done with a human skin model has shown, they induce new hairs.
Not surprisingly, treatments with 5 percent minoxidil work better than treatments with 2 percent minoxidil. A randomized clinical trial published in the American Journal of Clinical Dermatology in 2002 found that, in men with androgenetic alopecia, “5 percent topical minoxidil was clearly superior to 2 percent topical minoxidil and placebo in increasing hair growth.” The difference was actually pretty astounding — after 48 weeks, the men who used 5 percent minoxidil experienced 45 percent more hair growth than the men who used the 2 percent treatment.

Our panel of five people was unanimous in their choice – Shapiro MD. Developed by two leading dermatologists this patented formula has been proven to fight and even reverses hair loss in both men and women.  While some testers found the smell a bit herbal the overall consensus was that it was a fantastic color-safe shampoo and a moisturizing conditioner. In addition, we found their customer service was excellent and they honored their 60-day guarantee.  Shapiro MD designed their shampoo and conditioner with pharmaceutical-grade ingredients.  Shapiro MD’s mission is to develop health and beauty products using only clinically tested ingredients.
Pfizer Reports Positive AA Trial Results – A JAK3 inhibitor and a tyrosine kinase inhibitor (TYK2/JAK1) have shown statistically significant results in a phase 2a trial conducted by Pfizer. The company announced the results on September 15, 2018 at the European Academy of Dermatology and Venerology Congress. Subjects of the trial received oral doses of the drugs over a 6 month period. The TYK2/JAK1 inhibitor showed the greater efficacy, improving hair regrowth by 49.5 points on the Severity of Alopecia Tool scale, compared to an improvement of 33.6 points by the JAK3 inhibitor. However, Pfizer has apparently decided to move forward with its JAK3 inhibitor due to 2 adverse events in the TYK2/JAK1 inhibitor cohort during the trial. Pfizer’s JAK3 candidate, PF-06651600, was also recently granted Breakthrough Designation from the US FDA for treating alopecia areata. 
There’s also a women’s version (Women’s Rogaine Foam) — but a three-month supply costs $22 more online. The only difference between the two products are the instructions; women are instructed to apply once a day instead of twice. If you’re a woman who doesn’t feel like paying extra for marketing, the men’s product will suffice. A cheaper generic version is Kirkland Signature Minoxidil Foam, but with a longer history on the market and more customer testimonials, Rogaine is our first choice.
It never hurts to do a little bit of research when exploring treatment options for hair loss. But at some point, you'll probably want to talk with a physician so that you can get a professional opinion about how to combat hair loss. We don't recommend cutting corners by exploring cheaper homeopathic and all-natural remedies as an alternative. Drugs like finasteride and minoxidil are clinically proven to treat male pattern baldness and even reverse hair loss with a majority of men, and they’re approved by the FDA.
Follicum’s origins trace back to 2004, when two Lund University researchers targeting arteriosclerosis stumbled across a modified protein called osteopontin, which grew hair in mice. The researchers knew nothing about the hair-growth industry, but were quickly informed that there were big market demands, especially in Asia. “If you lose hair in Asia, you lose a lot of your credibility,” Jan Alenfall, the C.E.O. of Follicum, said. “This was really a serendipity finding.”
Skeptics (among them, Dr. Wesley) are starting to come around after a 2014 randomized double-blind study published in the American Journal of Clinical Dermatology found a “statistically significant” difference in hair density for women who used a laser comb compared with those who used a sham device. (“Comb” is something of a misnomer. The device looks like a hairbrush crossed with a cordless phone; it is glided back and forth across the scalp, roughly a half-inch at a time, usually about 15 minutes three times a week.)
Hair transplant surgery – which works by painstakingly moving grafts of hair (typically two to four follicles at a time) from the back of the head to the temples and crown, the first parts to drop – is becoming mainstream. Wayne Rooney was frank about his 48-hour, £30,000 follicular unit extraction at Harley Street Hair Clinic in 2011, and is widely credited with changing attitudes towards the procedure. Actor James Nesbitt had one as he feared he’d lose out on roles as a bald man. “It was something I struggled with,” he said, “and that was probably the vanity in me.”
Hair Surge contains three key ingredients: caffeine, ketoconazole, and saw palmetto. As already mentioned, all three are essential ingredients in any shampoo that’s truly targeted for hair growth. It doesn’t contain biotin, but you can always take biotin as a supplement if you absolutely feel that you have to have it. Besides, if you still have doubts that Hair Surge actually works, you can sift through the thousands of positive comments and testimonials about it online.

When it comes to organic products there are popular and high-quality brands you can choose from. Some chemicals can have quite harsh effects on longer hair, which means that they are not always suitable for women.  There are several organic brands that can be effective for those sensitive to these chemicals and in some cases can be more effective. Among the organic shampoos available are Reborn MAX and PhytoWorx.  Two brands that use caffeine are Apex Crown from Wick & Strom, and Ultrax Labs Hair Surge.


I am so happy with this product. I have thinning hair and have used many products in the past trying to at least stop it. I don't expect a miracle for it to grow back but I would love to just stop the hair falling out. Immediately after using this just one day I already noticed improvements. I was told my hair shined more, it was softer and also fuller. The hair falling out has improved a lot. I have not personally noticed hair growth yet but its only been 2 weeks now and I can say without a doubt it has made my hair healthier. I will be getting more for sure
Unlike The Big 3 Shampoo from Lipogaine, The Big 5 does not contain ketoconazole or copper peptides. However, it does have everything else The Big 3 has + 17 natural hair stimulating ingredients. We view this shampoo as more of a natural thickening shampoo whereas The Big 3 is going to be a little harsher on the scalp but better at nuking scalp DHT. Both shampoos are excellent products from trusted brand Lipogaine. We do know of some users that had had success rotating the Lipogaine shampoos and use The Big 3 every 3rd day or so and incorporate The Big 5 into their daily routine.

In this section we discuss some of the future hair loss solutions that will be coming out in the coming years. There are a few hair loss cures coming in or around 2020, and hopefully there will be a mass market solution. It is no surprise that ‘hair loss cures 2020’ is an extremely popular search term in Google. You’d think by that time we’d figure out how to stop hairs from falling out of heads.


In Vancouver, a Canadian company called RepliCel focusses on the hair follicle’s “dermal-sheath cup cells,” its C.E.O., Lee Buckler, explained. Buckler believes that DHT attacks these cup cells “like a parasite.” Like Histogen, RepliCel’s consumer product would be an injectable. The company would generate new versions of your cup cells, which would be implanted into your “affected area”—the places where your hair has fallen out. Boom: new hairs. (Theoretically.)
Hollywood has made movies about it. Industries have made billions from it. And if the volume of scripture is any indication, the Almighty God must have placed great value on his creation of the head of human hair. After all, He gave Samson—the strongest man of whom the Bible tells—his immense strength through his hair and declared a woman’s hair "a glory unto" her in the 11th chapter of 1 Chorinthians.
No one wants to deal with premature balding, thinning hair, or outright hair loss, but these conditions affect many people, both men and women. If you’re one of those people, understand that you don’t need to deal with the anxiety and embarrassment of losing your hair. There are many hair loss shampoos on the market that have been proven to work—and they can work for you, too.
“Re the post 10/17/18 I really liked your response to the request made by one of your readers to email companies asking for information. So I decided to do what you suggested and sent emails to Organ Technologies, Rivertown and Follicum (no particular reason) basically thanking them for their work and wishing them success with their products. Interestingly I received a very nice response from Organ Technologies which really surprised me. Correct me if I’m wrong but I think the sentiment is to be thankful and encouraging to what is being done appose to being negative that we have yet to get what we all want.”
“I also reached out to Histogen and Follicum a few weeks ago as well thanking them for all their hard work in bringing a safe and effective treatment to people all over the globe with hairloss issues and expressed how much we all value these companies. I held back from asking about market release as you had suggested. I received a very nice reply from Histogen.”
In the following decades, researchers learned that testosterone does not work alone. An enzyme converts testosterone into a substance called dihydrotestosterone, or DHT, which causes hair follicles to shrink. DHT attacks the dermal papilla, the “brain” of the hair follicle, and is the main cause of male-pattern baldness, which affects more than fifty million men in the United States and also—largely unremarked upon, but true—more than thirty million women.
As the name suggests, androgenetic alopecia involves the action of the hormones called androgens, which are essential for normal male sexual development and have other important functions in both sexes, including sex drive and regulation of hair growth. The condition may be inherited and involve several different genes. It can also result from an underlying endocrine condition, such as overproduction of androgen or an androgen-secreting tumor on the ovary, pituitary, or adrenal gland. In either case, the alopecia is likely related to increased androgen activity. But unlike androgenetic alopecia in men, in women the precise role of androgens is harder to determine. On the chance that an androgen-secreting tumor is involved, it's important to measure androgen levels in women with clear female pattern hair loss.

It looks like Organ Technologies’ recent announcement of its hair cloning progress has attracted some investment capital. Earlier this week, Organ Technologies issued a press release announcing that they have issued new shares to three new investors in exchange for approximately 590 million yen. That’s a lot of yen. In US dollars this converts to roughly $5.3 million, still a good haul. The press release mentions: 

There’s also a women’s version (Women’s Rogaine Foam) — but a three-month supply costs $22 more online. The only difference between the two products are the instructions; women are instructed to apply once a day instead of twice. If you’re a woman who doesn’t feel like paying extra for marketing, the men’s product will suffice. A cheaper generic version is Kirkland Signature Minoxidil Foam, but with a longer history on the market and more customer testimonials, Rogaine is our first choice.
NIZORAL???? What? Are u joking 🙃? NIZORAL make you loose hair , NIZORAL is not á shampoo is a synthetic imidazole antifungal drug used primarily to treat fungal infections. Ketoconazole is sold commercially as a tablet for oral administration (although this use has been discontinued in a number of countries), and in a variety of formulations for topical administration, such as creams (used to treat tinea; cutaneous candidiasis, including candidal paronychia; and pityriasis versicolor) and shampoos (used primarily to treat dandruff—seborrhoeic dermatitis of the scalp).
Hair is made up of the hair follicle (a pocket in the skin that anchors each hair) and the shaft (the visible fiber above the scalp). In the hair bulb, located at the base of the follicle, cells divide and grow to produce the hair shaft, which is made from a protein called keratin. Papilla that surround the bulb contain tiny blood vessels that nourish the hair follicles and deliver hormones to regulate the growth and structure of the hair.

This super-clean (and paraben- and sulfates-free, non-GMO, and vegan) shampoo zones in on the hair-saving supplement you’ve been hearing about for years: biotin. Nature’s Gate pairs its key ingredient with bamboo, a silica-packed scalp cleanser, and follicle-fortifying pro-vitamin B5. “I have thin hair that was breaking off and clogging my drain,” one reviewer wrote on Amazon. “No longer ... I may not have thick hair but it is stronger after using this shampoo.”
Jimenez, J. J., Wikramanayake, T. C., Bergfeld, W., Hordinsky, M., Hickman, J. G., Hamblin, M. R., & Schachner, L. A. (2014). Efficacy and Safety of a Low-level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-controlled, Double-blind Study. American Journal of Clinical Dermatology, 15(2), 115–127.
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Anagen is the growth phase. This lasts for about 3 - 5 years, where you can observe your hair growing half an inch every month. Full-length hair from this phase is about 18 - 30 inches long. Studies show that this phase may also be affected by other factors. Asian hair, for example, has been found to have a longer anagen phase. Weather is also a factor; hair growth can be faster in summer than in winter.

You may not know it, but stress affects your health in a number of different ways. It can zap your energy, make you feel physically ill, and even cause your hair to fall out. That’s right, stress plays a big role in contributing to thinning hair. On its own, stress-related hair loss is usually temporary and grows back over time. However, it can also speed up other forms of hair loss like male pattern baldness.
"The majority of men lose their hair not through stress, or bad diet, or lack of sleep, but through the genetic trait of male pattern baldness which is hard to treat through shampoos or supplements alone. Women lose their hair for very different reasons, but the argument still stands that a lot of the hair loss products on the market are just offering false hope. That said, there are a few that really work."
I started combining two of them right away – because they both had different ingredients that I really wanted. I combine the Hair Surge for the caffeine, ketoconazole, and saw palmetto, along with the Regenepure DR for the Emu oil. I use a bit of both every day – and though I haven’t noticed a lot of hair coming back in – I HAVE noticed that a whole lot less is falling out. I used to see lots of hair in the tub or in my hand after drying. Hopefully some baby hairs will start so show themselves soon.
“There’s people selling pills and creams and lotions and whatever else, and sometimes you can’t even trust what ingredients they have in there,” he warned us when we spoke to him over the phone. Key takeaway: The hair loss industry is crazy dishonest, so we eliminated any treatments (especially homeopathic methods) that aren’t based in concrete, peer-reviewed science.
In II Kings 2:23-24, the prophet Elisha is mocked by a gang of surly kids. The kids “said unto him, ‘Go up, you bald head! Go up, you bald head!’ ” Elisha “cursed them in the name of the Lord.” Promptly “two she-bears came out of the wood and tore forty-two of them.” Sometime later—in 2013—German researchers published a study indicating that men experienced hair loss as an “enormous emotional burden” that could lead to an “impaired quality of life” and “psychological disorders.” Inversely, one study has shown that people perceive men with bountiful hair as likely having big penises.
There seems to be some contention over whether hair products like hair sprays, hair gels and serums can lead to hair loss. What's true though is that frequent use of these products can damage your hair, either make it thinner or more prone to breakage. Limit the use of these products for those occasions when you absolutely need to. If you use hair products with harsh chemicals, especially hair sprays, wash your hair at night with a mild shampoo to get rid of the chemicals.

Observe proper hair care practices. The right hair care practices promote a healthy hair growth at the same time as it reduces and prevents hair damage such as breakage. Washing your hair with a mild, preferably natural, shampoo and conditioner with biotin should be an important part of your hair care routine. Go for cool showers instead because hot water can dehydrate your hair strands and lead to dry, thin hair that is easy to break. Lower temperature can help lock in moisture. Limit the use of the blow-dryer.


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This particular research which was published in the Nature journal showed that a synthetic version of sandalwood, called Sandalore, binds to the OR2AT4 receptor in hair folliles and prolongs their anagen (growth) phase. The hair follicles studied were treated in a petri dish. Paus has subsequently announced that a completed clinical trial of 20 female volunteers using a topical version of Sandalore showed a reduction of daily hair loss. There is also another larger clinical trial ongoing now which hopes to confirm the effect and announce results in early 2019. Paus has gone as far to say “there is even a chance that this might be able to bring the hair back.” We’ll keep our fingers crossed.
What’s equally frustrating for women is that their hair loss is not as clearly understood as hair loss in men and, according to an article in www.dermentz.org, “..presents itself quite differently from the more recognizable male pattern baldness which usually begins with a receding frontal hairline that progresses to a bald patch on top of the head.” The same article also says that it’s uncommon for women to follow a male pattern unless there is excessive production of androgens in her body.
2. Oil-rich conditioner. “Oils improve hair’s tensile strength,” says Paradi Mirmirani, a hair-loss specialist and dermatologist in Vallejo, California. In other words, oils make hair less likely to break under pressure, which is especially important for thinning hair that’s prone to snapping when brushed or styled. Mirmirani recommends using a conditioner fortified with natural oils, like Burt’s Bees Very Volumizing Pomegranate Conditioner, which contains avocado oil ($8), or Honest Company Conditioner with coconut oil ($10). That one’s got an added benefit: “Coconut oil has been shown to penetrate hair,” says cosmetic chemist Randy Schueller, so it makes your hair stronger from the inside out. (Just don’t load up on pure coconut oil. “You might overshampoo your hair to get it out, and then you’ll end up drying your hair and undoing any benefit,” says Fusco.)

Hair loss in alopecia areata occurs in three different patterns: patchy alopecia is circumscribed, oval-shaped, flesh-colored patches on any part of the body; alopecia totalis involves the entire scalp; and alopecia universalis involves the whole body. Evaluation of the scalp may reveal short vellus hairs, yellow or black dots, and broken hair shafts (which are not specific to alopecia areata). Microscopic examination of the hair follicles demonstrates exclamation mark hair (i.e., hairs that are narrower closer to the scalp and mimic an exclamation point; Figure 44). Nail pitting is also associated with alopecia areata.

The most common form of hair loss is androgenetic alopecia, or, in other words, male or female pattern baldness or hair loss. Androgenetic alopecia is genetic and affects an estimated 50 million men and 30 million women in the United States. Among white women in the U.S., an average of 19% are affected by female pattern hair loss, but that percentage increases with age. The prevalence is nearly doubled in Australia at 32% and much lower in Korea and China at < 6%. As of 2015, no studies had been done on the prevalence of female pattern hair loss in Brazil or Africa.

Hi Ive always had thin hair but about 15months ago I had baby and started to notice my hair was falling out now I’m looking for a solution because my hair is really thin now mostly on my right side and in the back I’ve never thought about how as having to find the right shampoo so I’m like by no means knowledgeable on this so do I just buy these and use them and see if it works for me or what other I’m sorry if im not making sense like where do I start
Biotin – Naturally found in many of the rich protein foods you eat including nuts, meats, eggs, etc. Biotin (or simply known as Vitamin B7) has been found in many studies to be linked directly to hair growth. Not only are men using this same vitamin to growth thicker beards, but Biotin is also prevalent in many of the leading natural hair loss shampoos on the market as you will see in just a minute. If you are going all-natural root, this ingredient should most definitely be included in the product you select.
In most cases though, it's all a matter of attitude. Being bald should not be a cause of stigma. It does not make you less of a person or less masculine, less virile, and less attractive and appealing. In fact, a clean shaven head is becoming a popular trend among men these days, and there are certainly many bald men who have managed to make themselves look clean, elegant and suave despite their hair loss. Learn to come to terms with it. It's hair loss, yes, but not brain damage. It does not affect your core.

Alopecia areata is an acute, patchy alopecia that affects up to 2% of the population with no difference between sexes 9 (Figure 3). Approximately 20% of affected patients are children.10 The etiology is unknown, but the pathogenesis is likely autoimmune. Patients may have a single episode, or they may have remission and recurrence. The diagnosis can usually be made clinically.
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Unfortunately nutritional supplements are hit and miss. While the risks of side effects go down which is attractive, clinical data is sparse. In most cases the individual has to conduct their own experimentation. At 6 months a pop for a fair trial, this is a time consuming process. Time is a very limited commodity especially in the hair loss game. As we know, it is easier to do preventative maintenance than reverse hair loss. Nevertheless, natural DHT inhibitors like saw palmetto and nettle have worked to prevent hair loss in some users.
HCell Inc. announced this week in a press release the addition of two new members to its Board of Directors. Robert P. Ryan PhD and Marlene Haffner MD PhD comprise the additions to the Board. HCell mentions in the release that the respective additions will be supportive to HCell through their combined experience in orphan drug development and FDA regulatory processes.
"Others are taking hair follicles out of human scalp and growing them with dermal papilla cells," Cotsarelis says. "If they grow in culture, you might be able to recombine them with skin cells and form new follicles. This would let you expand the number of follicles you get for a hair transplant. This may not be that far off -- five to 10 years, maybe. There's very good evidence you will be able to do that."

Examination of the scalp in patients with telogen effluvium typically shows uniform hair thinning. The presence of erythema, scaling, or inflammation; altered or uneven hair distribution; or changes in shaft caliber, length, shape, or fragility may suggest other diagnoses. Laboratory investigations are indicated if the history and physical examination findings suggest underlying systemic disorders (e.g., iron deficiency anemia, zinc deficiency, renal or liver disease, thyroid disease).
Besides cost considerations, a hair transplant is generally prescribed as a last resort for permanent hair loss problems. It is also not allowed for people under the age of 25, those with a continuing problem of hair loss, as well as those with other health conditions like uncontrolled diabetes, serious heart problems and hypertension. Patients whose hair loss is caused by other factors, such as a skin or scalp disorder or who suffer from a psychological condition that causes them to pull at their hair are not recommended for this procedure. Since the procedure requires taking a sample from the back of the head, those who do not have enough follicles from this section that can be used for transplant are not also eligible.

One of the longest running companies in the hair growth industry, Histogen, has been granted an IND from the US FDA for the use of its growth factor biologic (HSC) in female androgenic alopecia. The product will be called “HSC660” for use in women. IND stands for ‘investigational new drug’, and is a necessary permit that companies must obtain before starting clinical trials with a new medicinal substance. 
In-office laser light treatments or at-home handheld devices, such as the HairMax LaserComb, supposedly grow new hair by stimulating blood flow to the area (think: an amped-up version of a scalp-stimulating shampoo). Just don’t expect the device to make your noggin go from looking like George Costanza’s to Jerry Seinfeld’s. “These lasers won’t grow any new hair. If anything, they may just help you hang on to some of the hair that you already have a bit longer,” says Dr. Joyce.
The cause of female-pattern hair loss is unknown, but doctors said there is a strong genetic component. The risk can come from male or female relatives. Though it looks as if the hair is falling out, that's not really what's happening. Cotsarelis said hair follicles are becoming smaller and producing hairs that may be so small that you can't see them.  Women tend to retain more normal, thick hairs than balding men do.
McElwee is an associate professor in the Department of Dermatology and Skin Health at the University of British Columbia (UBC) in British Columbia, Canada and director of the Hair Research Laboratory in the Vancouver Coastal Health Research Institute (VCHI) at Vancouver General Hospital (VGH). A hair research scientist, McElwee is one of only a small group of research scientists worldwide who studies hair biology and associated diseases.
More good research coming from the University of Alabama at Birmingham shows that a certain gene affecting mitochondrial function can dramatically reverse signs of aging in mice. The aging factors which were shown to be reversible include skin wrinkles, gray hair, and hair loss. Next comes the important phase where the researchers continue forward to translate this discovery to human use. Full article on the front page.
Patel said the problem with those treatments is that they have not been subjected to large or head-to-head research. There's great variation in how doctors give the plasma treatments and in laser-based devices, so it's hard for patients to know whether they're getting a proven regimen. Nutrafol seems promising, he said, but he does not think that company-funded research showing its effectiveness has been replicated. He has not recommended it yet.
But, there’s an even more important step to take – your participation and contribution. The topic of “a cure for hair loss” or “a hair growth treatment”, for many of us, is one of the most important issues in our lives. What are you doing to support its success? I realize that question may not have previously crossed the mind for many. It’s here now. For a personal example, I’m not a scientist who creates molecules in a lab, so I decided I would organize the hair growth treatment news and spread awareness. It’s been a gratifying practice for me. 
If you're dealing with premature hair loss, you know how frustrating it can be to treat. What can be equally as frustrating is trying to find hair products that will actually help remedy thinning or breaking locks. To help you navigate the confusing world of hair loss, I reached out to Manhattan-based dermatologist Dr. Joshua Zeichner and used his recommendations to find the best shampoo and conditioner for hair loss.
Hair loss can be devastating to many men, but perhaps even more so for women, who have often suffered in silence. But, fact is, women make up nearly 40 percent of hair-loss sufferers in the United States. The psychological damage associated with hair loss is, for many women, extensive, especially in a society where hair-loss in men – though usually unwanted – is more or less an accepted fact of life.
2. Pyrithione zinc shampoo. Traditional volumizing shampoos will give the hair you have a lift so it looks fuller (we like the sulfate-free L’Oréal Paris EverPure Volume Shampoo, $8). But some research suggests shampoos with the antidandruff ingredient zinc pyrithione can mitigate hair loss that’s caused by conditions like dandruff, says Mirmirani. Try Head & Shoulders Deep Moisture Shampoo ($6), and use a conditioner without silicones — they can make hair appear limper, especially if it's applied near the roots (we like Love Beauty and Planet Coconut Water & Mimosa Flower Conditioner, $9).
There have also been studies on the effects of 1% pyrithione zinc shampoo and a 5% minoxidil solution. In one study, 200 men between the ages of 18 to 49 who experienced baldness between type III and type IV on the Norwood scale were given this treatment for a six-month period. They found that minoxidil, when used on its own, was approximately twice as powerful as pyrithione zinc at stimulating hair growth, but that both products were successful at increasing the amount of visible hair when used over a 26-week period.
“We are extremely pleased with the continued development of the patent portfolio we exclusively licensed from Columbia.  This new issuance continues to expand the breadth and depth of our JAK inhibitor intellectual property portfolio covering methods of use for certain JAK inhibitors for the treatment of hair loss disorders. The issuance of this patent is another step in the development of a robust patent portfolio relating to JAK inhibition and hair loss,”
Keranique is another line of products targeted towards women. They offer a complete system consisting of shampoos, conditioners, and topicals. Our testers found that it was one of the harshest shampoos and was not always color safe. Their topical foam contains Minoxidil which can irritate some scalps. Keranique hair products are safe to use and highly effective.  They also have an anti-dandruff shampoo that has received amazing reviews.
Managing hair loss is just as important as treating it. Now that we've talked about the different treatment options and cures available to reverse hair loss and promote increased growth, let's talk about how you can manage your condition and at the same time prevent further hair loss. The first is more psychological, while the second is more practical. 

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With those pinned down, it wasn’t hard to determine which don’t actually work. Pretty much all the “active” ingredients listed in ineffective treatments — from biotin and zinc to emu oil and saw palmetto — have never been proven, and are instead marketed based on logical-seeming correlations. It would make sense that biotin, a B vitamin readily found in hair, skin, and nails, could help hair grow more quickly. And caffeine is a stimulant that works in coffee, so rubbing some on your scalp might wake some of those sleepy follicles… right?

This is a short-term cure, applied while waiting for hair to grow, and therefore recommended for those with a mild to medium case of hair loss. In addition to being non-invasive, hair concealers and hair fibers are instant and affordable. Like wigs and hairpieces, they are used to effectively cover up balding spots while not getting in the way of growing hair. Compared to wigs, however, they are more natural looking and blend well with your natural hair, therefore drawing less attention when you're out in public.


Follicular Unit Extraction (FUE). In this method, instead of taking out a whole sample strip, small, individual follicle grafts are cut using a machine and then transplanted. The process is more tedious and more time-consuming, but has been known to have a higher recovery rate and there are no risks of scarring because no cuts and stitches are required.
Minoxidil typically comes in 2% and 5% dosage. With the former, hair growth is not visible up until the fourth month (16 weeks) of use, but it could be faster with the 5% dosage.This is most effective especially if you haven't been bald for more than 5 years, your bald patches are less than 10cm across, and most of all, if the bald spots still have some tiny, fine hairs. Studies found that people who have used minoxidil have observed at least minimal to moderate hair growth. The new hair is typically downy soft, but with continued use, it will grow in thickness as the rest of the hair.
Unfortunately, as with the aforementioned minoxidil, you’ll begin to lose your hair again if you ever stop taking Finasteride. Additionally, it may cause erectile dysfunction and other sexual problems in men although that’s uncommon. Men who experience these side effects from taking this pill can reverse them; however, that can take up to three months to occur.

Aloe vera. Aloe vera is one of the most traditional and common natural hair loss treatments. It is known to possess enzymes that promote hair growth and a healthy scalp by regulating the hair and scalp's pH level. Known as a hair miracle, it is also used to treat other hair/scalp conditions like scalp itchiness, scalp redness, and inflammation. It also helps in minimizing dandruff and making the hair shinier and stronger.


Hair multiplication. Similar to the idea of cloning, this treatment involves taking out donor cells from the hair follicles and then growing and multiplying them in a laboratory. Once sufficient samples have been multiplied, these hair cells are then injected into the bald patches to stimulate hair growth. As a relatively new treatment, hair cloning is still in its research phase.
Besides cost considerations, a hair transplant is generally prescribed as a last resort for permanent hair loss problems. It is also not allowed for people under the age of 25, those with a continuing problem of hair loss, as well as those with other health conditions like uncontrolled diabetes, serious heart problems and hypertension. Patients whose hair loss is caused by other factors, such as a skin or scalp disorder or who suffer from a psychological condition that causes them to pull at their hair are not recommended for this procedure. Since the procedure requires taking a sample from the back of the head, those who do not have enough follicles from this section that can be used for transplant are not also eligible.

Due to the concern of several readers, I’ve removed the link to the new Trinov website that has popped up on the net. For now, the website only contains an email address subscription box which really poses no issue to anyone who subscribed. At this time, it’s not confirmed who the actual owner of the new Trinov site is, so use your discretion until we find out more regarding this matter. Until more information is known the website will not be shared on Follicle Thought.
Recent update: “Breakthrough” in South Korea (11/21/17). We don’t want to get anyone’s hopes up prematurely, and we definitely hope this is not just another false alarm, but this recent discovery does seem to hold some promise. At best it would probably be 3-5 years out for wide availability, we think it’s still worth checking out. Professor Kang-Yell Choi of South Korean University Yonsei lead research indicating that they may have discovered a new protein that controls hair growth. The study in the Journal of Investigative Dermatology as well as a news article in the Korea Herald are good places to start reading about this new development.
RepliCel is a regenerative medicine company focused on developing autologous cell therapies (or therapies that involve one individual as both donor and recipient) that address conditions linked to a deficit of healthy cells required for normal healing and function. Located in Vancouver, British Columbia, the company has developed first-of-their-kind cell therapies that will, they hope, treat conditions that now affect 1 in 3 Americans: pattern baldness, aging and sun-damaged skin, and chronic tendon degeneration.

Dupilumab is FDA approved for treating eczema aka atopic dermatitis and sold under the brand name Dupixent.  As the story goes, a patient with alopecia totalis (a form of areata which leaves a person’s head completely bald) was being treated for eczema by the drug Dupixent. After 6 weeks the patient first began to notice progress in terms of hair growth and at 7 months she had noticeable pigmented hair growth on her scalp. Notably, the patient stopped taking the dupilumab for a period of time and noticed her growth subsided; when she began taking the drug again the hair improved once more. This provides another useful therapy option for patients seeking treatment for AA. One would imagine a topical version would be worthwhile to investigate.
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