Perhaps the most important area of hair loss research that I have not yet covered on this blog relates to the Sonic Hedgehog (SHH) protein and signaling pathway.  This Shh pathway is used by cells to communicate with each other. While the sonic hedgehog protein has numerous critical effects on a developing human embryo (brain, craniofacial, lungs, teeth and more), it also continues to be important in adulthood when it controls certain stem cell division activities.
And, for all of these collective efforts, Christiano reminded me, the only things that have really worked were discovered accidentally. Soon to join minoxidil and finasteride will be Xeljanz, or tofacitinib: originally developed for rheumatoid arthritis, it has remarkable effects on hair growth for patients with alopecia areata, an autoimmune disorder that causes patients to lose hair in big patches over their entire bodies.

What's to know about alopecia areata? Alopecia areata is an autoimmune disorder that usually results in unpredictable, patchy hair loss. Approximately 7 million people in the U.S. have alopecia areata, and it can affect anyone of any age or gender. There is no cure for alopecia areata although some treatments are available to help hair regrow more quickly. Read now


This moisturizing double-duty product is incredibly well rated (and you don’t even have to pay the pink tax to boot). Soy proteins and shea butter add silky strength, while scalp-tingling peppermint and rosemary provide minty freshness and lift at the root. “The thickening properties of the shampoo are great at this price point, so if you have thin or thinning hair, this will add some volume,” wrote one reviewer. “I also noticed that this is the first shampoo/conditioner shampoo that tends to actually condition your hair."

But here's one thing that most people miss when they talk about hair loss: It's part of the natural process of the hair growth cycle. Shedding hair is normal, and losing hair as we age is normal. However, there are instances when we are shedding hair at an abnormally faster rate than usual - and this is something that we have to pay attention to. It's also perfectly understandable and acceptable that some people would like to reverse the hair loss that comes as part of the aging process.


This video is equally hilarious. Once again, there is inspiration here. Deion had a 5,000+ FUE last year and received good results from it. But he’s not done yet, he has the resources to have another procedure and get as close as he can to the result that he really wants, so he did. Surely, he’s just about maxing-out his donor area now. Once again, congratulations to Deion for pursuing his hair growth goals. Enjoy the video and have a big laugh. OOOOeeee.
But the male propensity to internalise their feelings often leaves them particularly vulnerable. “I know guys who have changed their career paths because of their hair loss,” says Kobren. “I know a lawyer who began delivering potato chips so he could wear a cap to work. I know an NYPD officer who was so devastated by a bad transplant, he had to retire and he ended up on disability benefit.”

The average person loses 50 to 100 hairs per day naturally due to this cycle. But if the process is interrupted at any stage—for example, if the follicle doesn’t come back out of resting mode or starts to shrink—hair loss and hair thinning can result. Interruptions to the cycle can be caused by hormones, stress, poor diet, chemical hair treatments, certain medications, and, of course, good ol' genetics.

Researchers from the NIH and the University of Alabama, Birmingham have discovered a connection between the body’s innate immune regulation and hair graying. It was found that the transcritpion factor known as MITF, which plays an important role in melanocyte function, also plays a major role in hair graying. When the body’s immune system is dealing with a pathogenic infection such as bacteria or virus, molecules called interferons will send out signals to the body to take action against the pathogen. If MITF loses control of interferon response in melanocyte stem cells (due to an immune system response), hair turns gray. Essentially, immune system response may contribute to the process of hair graying according to the study.

Disruptions in the normal length of each phase, which can cause hair loss and hair thinning, may be the result of a number of internal and external stimuli. These are also what we call the triggers and causes of your hair loss. As a quick example, dieting can leave the body stressed and in need of important nutrients. Because of this stress, hair growth may be cut shorter than usual and there is an early onset of telogen or shedding of hair.


Aside from medication and lasers, some opt for hair transplants — a procedure where hairs are removed from another part of your body and then transplanted to the thinning or balding areas. Does it work? In a word, yes. Research suggests that most hair transplant recipients report are "very satisfied" with their results. While successful, transplants are also far more expensive than medications, foams, or lasers with costs averaging anywhere from $4,000 or $15,000.
“I was 21 when I noticed my hair getting thinner,” says David Anderson, 45, who has had seven hair transplants. He is now senior patient adviser at the Maitland Clinic in Liverpool, one of the country’s leading hair transplant clinics, where he raises awareness of the vulnerability of sufferers. “It was devastating. It completely consumed my existence. Now, I really regret that. But time and again, I’m meeting patients going through the same anxieties. It’s an epidemic. A lot of people don’t understand how it can make you feel.”
Choose the right shampoo based on its healthy and all-natural active ingredients, such as those found in Veta. These products do work on your thinning and shedding hair. And if you’re wondering, “How fast will I regrow hair with a hair growth shampoo?” Well, that again depends on the cause of your hair loss: genetics, lifestyle choices, environmental triggers, etc... but also on the product’s composition and concentration of active ingredients. Veta has the highest concentrations of both follicusan and trichogen, which is why Veta products work.
It never hurts to do a little bit of research when exploring treatment options for hair loss. But at some point, you'll probably want to talk with a physician so that you can get a professional opinion about how to combat hair loss. We don't recommend cutting corners by exploring cheaper homeopathic and all-natural remedies as an alternative. Drugs like finasteride and minoxidil are clinically proven to treat male pattern baldness and even reverse hair loss with a majority of men, and they’re approved by the FDA.
Buckler said it started in 2003 with the academic research of Hoffmann and McElwee at the University of Marburg in Marburg, Germany. At the time they were trying to understand what was happening in the hair follicles of people suffering from androgenetic alopecia—a common form of hair loss in both men and women—or the underlying cause of hair loss.
Hair concealers and hair fibers. These are one of the newest cosmetic answers to hair loss. As the name suggests, these products are applied on the scalp or hair to camouflage hair loss and give the appearance of fullness to thinning hair. Some of these are applied directly on the scalp, while others (hair fibers) are attached to the hair, much like hair extensions, to add volume.
Finally, if these tests come back normal, your dermatologist may suggest a scalp biopsy of a couple of two-millimeter sections taken from your scalp under local anesthesia ($400 and up). It can determine whether genetic hair loss, telogen effluvium (a condition in which hair falls out from stress or rapid weight gain), or a disease (such as lupus) is the cause of your shedding, and your dermatologist can treat you accordingly.
But here's one thing that most people miss when they talk about hair loss: It's part of the natural process of the hair growth cycle. Shedding hair is normal, and losing hair as we age is normal. However, there are instances when we are shedding hair at an abnormally faster rate than usual - and this is something that we have to pay attention to. It's also perfectly understandable and acceptable that some people would like to reverse the hair loss that comes as part of the aging process.
According to practitioners of traditional Chinese medicine, hair health is tied to two things: kidney energy and the blood, which nourish the hair. The solution: acupuncture and Chinese herbs. While there isn't a lot of hard science to back this up, Maureen Conant, a TCM practitioner at Full Bloom Acupuncture in Seattle, says that she's seen women's hair stop falling out and then gradually regenerate after a few months of weekly treatments.
A clinician diagnoses female pattern hair loss by taking a medical history and examining the scalp. She or he will observe the pattern of hair loss, check for signs of inflammation or infection, and possibly order blood tests to investigate other possible causes of hair loss, including hyperthyroidism, hypothyroidism, and iron deficiency. Unless there are signs of excess androgen activity (such as menstrual irregularities, acne, and unwanted hair growth), a hormonal evaluation is usually unnecessary.
“There’s the ‘I don’t date bald men’ line – hard to argue with, but still an injury to one’s pride.” Then there are a surprising number of people who call out “baldie!” in the street, or equate a shaved head with homosexuality and/or neo-Nazism. “I’ve had baldist/homophobic abuse in the street a couple of times and I’ve even been asked on the Tube: ‘Are you BNP, mate?’ When I expressed bewilderment at this, I was told: ‘It’s the hair, innit.’”
Minoxidil and oral finasteride are the only treatments currently approved by the U.S. Food and Drug Administration for the treatment of androgenetic alopecia. Both of these drugs stimulate hair regrowth in some men, but are more effective in preventing progression of hair loss. Although there are a number of other treatments listed in various texts, there is not good evidence to support their use.8
1. Minoxidil. It’s the only FDA-approved topical nonprescription medication that can claim to regrow hair — and it should be part of any hair-loss plan if you have serious thinning, says Rogers. Minoxidil has loads of research to back it, but it requires commitment. If you quit using it, your hair will start to lose ground again. Use a 5 percent strength, like Women’s Rogaine 5% Minoxidil Foam ($30), once daily to see results in three to four months, says Rogers.

Finasteride comes in the form of a tablet and works by inhibiting the formation of DHT, a hormone which permanently damages hair follicles. They are only appropriate for use as a male pattern baldness treatment and must be taken once a day for 3-6 months for the effects to be seen. In one study, 90% of men with mild to moderate hair loss saw positive effects after taking finasteride for six months, with hair loss stopping and in some cases even reversing. Finasteride is therefore very effective while it is being taken, but will not continue to have an effect after treatment has ceased. Around a year after you have finished taking Propecia or finasteride, you can expect your hair loss to have resumed and any hair regrowth to have fallen out. For this reason, they are not cures so much as effective ongoing treatments.
Would there be any harm/benefit in combining the use of two hair-loss prevention shampoos, to take advantage of different ingredients and functions? Mainly Nizoral, at the twice a week recommendation, plus the Argan Oil Shampoo twice a week? I have somewhat oily hair and do get dandruff from time to time, but I do feel after washing my hair, it can feel dry and stiff. Just wondering if a combination of the two (one for dandruff, and one for healthy, thicker hair) might prove effective. Also, would you have any recommendations on a combo? Thanks!

Minoxidil (Rogaine, generic versions). This drug was initially introduced as a treatment for high blood pressure, but people who took it noticed that they were growing hair in places where they had lost it. Research studies confirmed that minoxidil applied directly to the scalp could stimulate hair growth. As a result of the studies, the FDA originally approved over-the-counter 2% minoxidil to treat hair loss in women. Since then a 5% solution has also become available when a stronger solution is need for a woman's hair loss.


Like the long-suffering friend who inspired her to undergo the procedure, Ms. Telford quickly saw an improvement in her hair. New hair growth usually take at least four months, but at the two-month mark, she has already spotted some baby hairs. “Not a gazillion,” she said, “but it’s a start.” She’s planning to return for follow-up treatments every six months, and has high hopes of ditching the wigs and wearing her hair in a pixie.

The Holy Grail remains a drug that will promote regrowth, but this might not be so far away. Earlier this year, Manchester University announced that an osteoporosis drug had been found to have “dramatic results” promoting hair growth when applied to tissue samples in pre-clinical trials. The resultant frenzy left the PhD student responsible, Dr Nathan Hawkshaw, a little dazed. “Every other week, something comes out about hair loss and it doesn’t generate as much media coverage as what I experienced,” he grumbles. He’s in this for the science – there aren’t many fields where you get to mess around with real human tissue – but such is the distress caused by hair loss and such is the potential customer base that interest is always high.
Aclaris Therapeutics has announced on March 9, 2018 that the US Patent and Trademark Office has issued their company U.S. Patent No. 9,895,301, for methods related to  the use and administration of a certain janus kinase (JAK) inhibitor for treating hair loss disorders. This patent covers the treatment of both alopecia areata as well as androgenic alopecia.

“We are extremely pleased with the continued development of the patent portfolio we exclusively licensed from Columbia.  This new issuance continues to expand the breadth and depth of our JAK inhibitor intellectual property portfolio covering methods of use for certain JAK inhibitors for the treatment of hair loss disorders. The issuance of this patent is another step in the development of a robust patent portfolio relating to JAK inhibition and hair loss,”
A clinician diagnoses female pattern hair loss by taking a medical history and examining the scalp. She or he will observe the pattern of hair loss, check for signs of inflammation or infection, and possibly order blood tests to investigate other possible causes of hair loss, including hyperthyroidism, hypothyroidism, and iron deficiency. Unless there are signs of excess androgen activity (such as menstrual irregularities, acne, and unwanted hair growth), a hormonal evaluation is usually unnecessary.
Researchers from UCLA in the lab of Jing Huang have recently shown that certain molecules which activate the cellular process known as autophagy also drive hair follicles into the anagen (growth) phase. The researchers studied different metabolite molecules and other molecules which are FDA approved and on the market as drugs. The most recognizable drugs from the study were metformin and rapamycin, one is a diabetes medicine and the other an immunosuppressant. Dr. Huang says her lab is looking to study these drugs for human hair growth soon. In my opinion, results from that study are something to look out for. Full article on the Articles page.
DS Laboratories have covered all the bases with this shampoo, circulation, cleansing action, and anti-DHT properties. It starts acting on the first day of use but most users of the shampoo start to see results after about 4-6 months of use. When you wash with the shampoo, you leave it on the scalp for about 2 minutes before rinsing to allow you scalp to absorb all the ingredients. For the best results, DS Laboratories suggest using Revita at least 5 times per week.
Other options include microneedling ($1,200 and up per treatment) and platelet-replacement therapy (also $1,200 and up per treatment), which are usually offered in conjunction. Your scalp will be numbed first so you don’t feel the pinpricks involved in microneedling. They promote hair regeneration by spurring wound healing, and platelet-replacement therapy involves injecting growth factors into those wounds. “Combination therapy typically works better than monotherapy and usually yields results after three monthly treatments,” says Sadick, and should be teamed with an at-home minoxidil treatment.
Late last week, HairClone officially unveiled its crowdfunding campaign with the Euro-based crowdfunding company Capital Cell. HairClone is offering equity based crowdfunding, which means anyone who makes an investment (£500 minimum) owns equity in the HairClone company. Full details on the campaign are listed in the latest HairClone article on the main page of Follicle Thought.
I am a 45 yr female that has experienced hair loss to the point of having to hire a plumber twice (over 3 years) to unclog our drain in our main bathroom although I am pretty cautious about picking up my hair. My ponytail is about 1/2 the size that it was 5 years ago. i had excessive hair loss after the birth of my last 2 of 3 children. It is noticeably thinner although my employees, friends and husband seem to think my hair is thick. I can see my scalp very easily. (No patchy alopecia though) I started using viviascal professional strength about 2 months ago and hair surge shampoo only about 2 weeks ago. The bottle has about 1/3 left and i am wondering what is to be expected from this product. I have to use at least 8 pumps ( it seems to be double the volume of normal shampoo that i use) and it does not seem to later that well until after a min or so. Additonally i am using the hair surge supplement. When should i see less hair falling out? When should i expect visible results. Any other suggestions? I know it says to use 5 of 7 days, but i use it daily to make sure i am getting the full benefit ( if any) from this product. Currently i am looking at 100 buck a month for the shampoo alone if i keep this up. Any advice is welcome. Thanks
But here's one thing that most people miss when they talk about hair loss: It's part of the natural process of the hair growth cycle. Shedding hair is normal, and losing hair as we age is normal. However, there are instances when we are shedding hair at an abnormally faster rate than usual - and this is something that we have to pay attention to. It's also perfectly understandable and acceptable that some people would like to reverse the hair loss that comes as part of the aging process.

Hair spa. A hair spa treatment is one of the most convenient, non-invasive, not to mention, most rejuvenating ways to treat hair loss and promote healthy hair growth. Besides hair loss, it has also been known to address other hair issues like dandruff, split ends, and dry and damaged hair. There are many forms of hair spa treatment depending on what's offered at the salon, but it generally includes an oil massage of the scalp, shampoo and deep conditioning. The whole process helps in blood circulation, bringing the needed nutrients to the follicles, and activates the glands to produce oil.

Anagen is the growth phase. This lasts for about 3 - 5 years, where you can observe your hair growing half an inch every month. Full-length hair from this phase is about 18 - 30 inches long. Studies show that this phase may also be affected by other factors. Asian hair, for example, has been found to have a longer anagen phase. Weather is also a factor; hair growth can be faster in summer than in winter.

Perhaps the most important area of hair loss research that I have not yet covered on this blog relates to the Sonic Hedgehog (SHH) protein and signaling pathway.  This Shh pathway is used by cells to communicate with each other. While the sonic hedgehog protein has numerous critical effects on a developing human embryo (brain, craniofacial, lungs, teeth and more), it also continues to be important in adulthood when it controls certain stem cell division activities.
Finding the best hair loss shampoos for men can sometimes feel like a wild goose chase. In this article, We have done the heavy lifting for you and identified the best options and put them alI in one place. Interested in keeping that silky mane flowing strong? Shampoo is a big part of how you care for those luscious locks and the scalp underneath. It makes sense that you wouldn’t want to use just any shampoo, especially if you’re battling balding. Your hair deserves better. Read on my friend.
Contact immunotherapy. Another drug that can be administered for cases of alopecia areata is contact immunotherapy and is recommended for severe cases. Diphenylcyclopropenon (DPCP) is applied on the scalp every week, and the dosage of the drug is increased over time until a mild allergic reaction is observed, which signals that the drug is taking effect. Regrowth may be observed within three months from the beginning of treatment.
Disruptions in the normal length of each phase, which can cause hair loss and hair thinning, may be the result of a number of internal and external stimuli. These are also what we call the triggers and causes of your hair loss. As a quick example, dieting can leave the body stressed and in need of important nutrients. Because of this stress, hair growth may be cut shorter than usual and there is an early onset of telogen or shedding of hair.
David made this claim back in 2000. But fast-forward a few years and his enhanced compensation strategy begins to look a little quaint. Androgenetic alopecia, or male pattern baldness, afflicts about half of all men aged 50 and they can’t all reinvent the sitcom. And significant advances in the £3bn hair regrowth industry mean that they have other, seemingly easier, options. The man who is “ideally bald” (to use Vladimir Nabokov’s description of his comic hero, Pnin) may soon become a rare sight. 

If a pregnant woman comes in contact with crushed or broken Finasteride tablets, wash the contact area right away with soap and water. If a woman who is pregnant comes into contact with the active ingredient in Finasteride, a healthcare provider should be consulted. If a woman who is pregnant with a male baby swallows or comes in contact with the medicine in Finasteride, the male baby may be born with sex organs that are not normal.
Late last week, HairClone officially unveiled its crowdfunding campaign with the Euro-based crowdfunding company Capital Cell. HairClone is offering equity based crowdfunding, which means anyone who makes an investment (£500 minimum) owns equity in the HairClone company. Full details on the campaign are listed in the latest HairClone article on the main page of Follicle Thought.
Kuntzman described the “snake oil” era of hair restoration, in the early twentieth century, when salesmen offered nonsense treatments, often with horrific results. One involved “cylinders of skin taken from the abdomen and sewn into your scalp to function as a sort of belt loop” for new hairs, Kuntzman said; another used paraffin injections that left some customers with lifelong horn-like head bumps. Most of the really ugly stuff ended in 1938, when the Food and Drug Administration began regulating the industry.
Try balayam yoga. Balayam yoga (also called balam yoga) is an ancient acupressure exercise associated with hair growth. It comes from the Hindu words, Bal, which means hair, and Vyayam meaning exercise. The exercise involves rubbing the fingernails on both hands together to stimulate activity in the scalp. It has been known to help cure pattern baldness in men and women if done correctly and frequently over a long period of time.
3. Surgical hair replacement. If you opt for hair transplantation (which runs $5,000 and up), your dermatologist or hair-replacement surgeon will remove single hair follicles from the back of the head, near the nape of the neck, where your hair is fullest. Once those follicles are harvested, they are then dissected and reimplanted into an area of the scalp where hair is thinning. The procedure takes anywhere from three to six hours, and newly implanted hair will usually begin to grow on its own 3 to 12 months after the treatment session. Traditionally, hair transplantation required removal of an entire strip of scalp, Sadick says, but this new follicle-by-follicle technique looks more natural when it heals and allows patients to get heads of hair as dense-looking as before they started losing it.
This is an organic shampoo which contains the key ingredient Biotin, often said to topically strengthen existing hair strands. Pura d’Or shampoo also has a proprietary ingredient based on Saw Palmetto, which supposedly blocks DHT – the key culprit in pattern baldness. Some users say it hasn’t just protected their existing hair but has promoted the growth of healthy new hair as well.
DH—or as it’s less commonly known, Dihydrotestosterone—is the bodily byproduct that (in the TL;DR explanation) shrinks hair follicles until they’re so thin and short they just fall out. Keranique’s unique blend includes a DHT-inhibitor, which penetrates the scalp and follicles to deliver a keratin amino complex, developed to add resilience and protection. This one can contribute to improved texture, healthier strands, and yes, even new growth.
"We developed a protocol to drive human pluripotent stem cells to differentiate into dermal papilla cells and confirmed their ability to induce hair growth when transplanted into mice," said Prof. Terskikh. The next step in their research is "to transplant human dermal papilla cells derived from human pluripotent stem cells back into human subjects."
Before deciding on the best shampoo for thinning hair, you'll want to figure out what the underlying cause is. According to Dr. Zeichner, the most common causes of hair loss are chronic tension on the hair follicles, breakage from chemical process treatments — which include perms, relaxers, or hair dye — and severe dandruff or scalp psoriasis. Chronic medial conditions, such as autoimmune diseases, are also a common reason for hair loss, so if you're unsure of the cause, it's important to see a doctor to rule out other possible conditions.
Hair follicles on our head are at various stages of this hair growth cycle, so that while some hair follicles are in the last stages, others are just beginning their anagen phase, while others still are in the middle of the hair growth cycle. It's because of these varying stages of growth that our hair doesn't fall out all at once. Instead, you only shed about 50 - 100 strands a day - this is the normal rate of shedding hair.
“I was 21 when I noticed my hair getting thinner,” says David Anderson, 45, who has had seven hair transplants. He is now senior patient adviser at the Maitland Clinic in Liverpool, one of the country’s leading hair transplant clinics, where he raises awareness of the vulnerability of sufferers. “It was devastating. It completely consumed my existence. Now, I really regret that. But time and again, I’m meeting patients going through the same anxieties. It’s an epidemic. A lot of people don’t understand how it can make you feel.”
You always hear these stories about people who take a homeopathic approach to fighting baldness. It’s always some off-the-wall remedy like smearing a paste of ginger and cayenne pepper on your scalp three times a day or eating a special type of ginseng farmed only in a rural village in Tibet. We'll go on the record to say that it's highly unlikely that these remedies work at any level.
It can be safe provided you use registered, regulated healthcare or pharmaceutical services. LloydsPharmacy Online Doctor offers both Propecia and finasteride for men suffering from male pattern baldness through a safe and discreet online prescription service, and you will be able to order minoxidil or Regaine through our online shop or in one of our pharmacy stores.

I feel inspired to share on the Updates thread a few uplifting comments I received from readers in the past week. Following my admonition to a previous commenter that sending out short, supportive emails to hair growth companies (without asking for extra information that you know they are not ready to share) would be a worthwhile endeavor and boost morale, I received some encouraging responses from two frequent visitors of this site who followed through on the idea. Their comments are shared below. 🙂

Know the different types of wigs. Synthetic wigs are easy to style and are less expensive than human hair wigs. On the other hand, wigs made from human hair have a more natural look and feel, and are more preferred by those with permanent cases of hair loss. Though they take longer to style, human hair wigs are worth an investment if you plan on wearing it for a relatively long period of time.
You might be surprised to know that some of those shampoos, conditioners, and styling agents have harsh chemicals that do a number on your hair. You may want to consider switching to softer hair care products that are designed to slow down hair thinning in men. DHT-blocking shampoos and conditioners containing ingredients such as ketoconazole and pyrithione zinc have shown some promise in helping reverse hair loss by potentially disrupting the production of DHT, the hormone linked to male pattern baldness. These

There’s also a women’s version (Women’s Rogaine Foam) — but a three-month supply costs $22 more online. The only difference between the two products are the instructions; women are instructed to apply once a day instead of twice. If you’re a woman who doesn’t feel like paying extra for marketing, the men’s product will suffice. A cheaper generic version is Kirkland Signature Minoxidil Foam, but with a longer history on the market and more customer testimonials, Rogaine is our first choice.


Drugs normally used for rheumatoid arthritis and bone marrow cancer, they are now being studied for their uses as a hair growth medicine. These are a new class of medicines labeled as JAK inhibitors. In one study, 6 out of 9 patients dramatically went from bald to a full head of hair after taking Ruxolitinib for 5 months. In another study several subjects were able to regrow full heads of hair. Unfortunately, sustained use of such drugs will have severe side effects. Many of these concerns would be side stepped if a topical formula could be developed. Researchers at the Department of Dermatology and Genetics and Development at Columbia University Medical center are now studying other JAK inhibitors in placebo controlled studies.
What is one thing you can do to help new hair growth treatments become a reality? Be creative. Your activity, whatever it might be, will give you a sense of empowerment. You will be contributing to the goal of new hair growth treatments becoming available in the world. How could you feel apathetic or helpless when you are taking the initiative to get involved? Please share in the comments of this page your ideas or practices for how you personally choose to contribute to the success of new hair growth treatments becoming a reality. Remember, every idea or action is worthwhile and supports the outcome. Be authentic and best wishes. Thank you
This super-clean (and paraben- and sulfates-free, non-GMO, and vegan) shampoo zones in on the hair-saving supplement you’ve been hearing about for years: biotin. Nature’s Gate pairs its key ingredient with bamboo, a silica-packed scalp cleanser, and follicle-fortifying pro-vitamin B5. “I have thin hair that was breaking off and clogging my drain,” one reviewer wrote on Amazon. “No longer ... I may not have thick hair but it is stronger after using this shampoo.”
Researchers from South Korea have identified a new peptide called PTD-DBM which exhibits wound healing and hair regeneration effects in preclinical studies. The research is being led by Professor Kang-Yell Choi of Yonsei University. Choi’s team identified the peptide PTD-DBM which targets a protein called CXXC5. The interaction of these two proteins leads to stimulation of the Wnt pathway, which then initiates hair follicle neogenesis. Choi hopes to develop this peptide further into a potential hair growth drug candidate. A research paper about these findings was put out by the team earlier this year. Source article about this development here.

Laser light therapy is not a baldness solution, and the HairMax takes a time commitment: You have to use the product for 15 minutes a day, three days a week and you have to keep using it indefinitely to get results. Still, laser light therapy has no major side effects, and may be best for men who have noticed some increased shedding and want to maintain more of the hair they have on their head.


Contact immunotherapy. Another drug that can be administered for cases of alopecia areata is contact immunotherapy and is recommended for severe cases. Diphenylcyclopropenon (DPCP) is applied on the scalp every week, and the dosage of the drug is increased over time until a mild allergic reaction is observed, which signals that the drug is taking effect. Regrowth may be observed within three months from the beginning of treatment.
Post surgery care is important if you've undergone a hair transplant or surgery. Expect some swelling of the face and on the scalp a couple of days after the procedure. To fast track hair growth, you may be asked to use Minoxidil or Finasteride. Saline is applied on the grafts for a few days, while you will be prescribed to use a diluted shampoo that is softer and less harsh on the scalp. Hair growth in the transplanted areas becomes visible in three - six months.
The law enhances the FDA’s ability to modernize clinical trial designs and clinical outcome assessments, which will perhaps speed the development and review of novel medical products, including medical countermeasures. The Cures Act also directs the FDA to create so-called “intercenter institutes” to help coordinate  activities in major disease areas between the drug, biologics and device centers and improves the regulation of combination products. An example of one of these centers is the Oncology Center of Excellence.
I hope you’re all having a good Friday and feeling good out there. Two weeks ago I posted my first “Feel Good Friday” update which contained a hilarious video of Deion Sanders showing off his new hairline from a 5,000+ FUE procedure he had in 2017. That video is now unable to embed because its owner changed his account to private. Coincidentally, a week after I shared that video I noticed that Deion posted a new video to his own Instagram account of him going back to his clinic for another FUE hair transplant to “comeplete his comeback”, in his own words.

Where is the bald spot? What exactly are the dimensions of this bald spot? It’s all so stupid, so tiringly stupid. In May, Trump’s former personal physician, Harold Bornstein, revealed that Trump had sent people to seize all of his personal health records. Bornstein called it a “raid” that left him feeling “raped, frightened, and sad.” He also claimed that it was revenge for having revealed to the media that Trump was on Propecia.
Patients with hair loss will often consult their family physician first. Hair loss is not life threatening, but it is distressing and significantly affects the patient's quality of life. The pattern of hair loss may be obvious, such as the bald patches that occur in alopecia areata, or more subtle, such as the diffuse hair loss that occurs in telogen effluvium. As with most conditions, the physician should begin the evaluation with a detailed history and physical examination. It is helpful to determine whether the hair loss is nonscarring (also called noncicatricial), which is reversible, or scarring (also called cicatricial), which is permanent. Scarring alopecia is rare and has various etiologies, including autoimmune diseases such as discoid lupus erythematosus. If the follicular orifices are absent, the alopecia is probably scarring; these patients should be referred to a dermatologist. This article will discuss approaches to nonscarring causes of alopecia.
Finasteride inhibits an enzyme that converts testosterone to DHT, or dihydrotestosterone, the hormone that causes hair loss in men, and unlike minoxidil, this drug can actually help hair grow back, as well as prevent further loss. All you have to do is take one pill a day, and according to Dr. Evan Rieder, dermatologist in the Ronald O. Perelman Department of Dermatology at NYU Langone Health, two-thirds of men taking this treatment will see improvements in hair density over time.
Other therapies for the treatment of alopecia areata include topical mid- to high-potency corticosteroids, minoxidil, anthralin, immunotherapy (diphenylcyclopropenone, squaric acid dibutylester), and systemic corticosteroids.12 Currently available therapies often yield unsatisfactory results, and some clinicians rely on the high rate of spontaneous remission or recommend a hairpiece or wig if remission does not occur.13
The cause of female-pattern hair loss is unknown, but doctors said there is a strong genetic component. The risk can come from male or female relatives. Though it looks as if the hair is falling out, that's not really what's happening. Cotsarelis said hair follicles are becoming smaller and producing hairs that may be so small that you can't see them.  Women tend to retain more normal, thick hairs than balding men do. 

Examination of the scalp in patients with telogen effluvium typically shows uniform hair thinning. The presence of erythema, scaling, or inflammation; altered or uneven hair distribution; or changes in shaft caliber, length, shape, or fragility may suggest other diagnoses. Laboratory investigations are indicated if the history and physical examination findings suggest underlying systemic disorders (e.g., iron deficiency anemia, zinc deficiency, renal or liver disease, thyroid disease).
Hair loss shampoo probably won’t help you defeat hair loss on its own, but it certainly should be used as another weapon in your arsenal. Many of these products do contain ingredients that are beneficial for hair loss and scalp health—every little bit helps. Let’s face it, you have to wash your hair with something and that something might as well aid in hair loss prevention.
At first the researchers conducted studies using cyclosporine A, an immunosuppressant. One of its side effects is hair growth. That set of testing led them to the SFRP1 protein and the discovery that the protein blocks hair growth. But cyclosporine A has too many side effects to pursue further testing, which is why they set their sights on the osteoporosis drug.

The combination of silent suffering, public shame and poorly understood science makes hair loss sufferers easy prey – type “hair loss” into Google and you’ll see what I mean. Kobren tells me that he had to remove the personal messaging function on the Bald Truth message board, as users were being bombarded by scams. Meanwhile, the higher visibility of celebrity transplants means that baldness is at risk of being seen as a sign of poor self-care. Many treat surgery lightly – and enter into punitive financing deals. One of Kobren’s recent guests was The Only Way is Essex star Maria Fowler, who complained that surgery at the controversial KSL Hair in Glasgow left her with an unnatural hairline. “She ended up having a hair transplant because her fiancé was having one. She had always thought her hairline was too high. She went in like she was having her nails painted – and it destroyed her life.”
NFL Hall of Fame player Deion Sanders has recently undergone a hair transplant. He has not been shy about discussing it publicly and over the last several weeks has actually continued to put out a slew of hilarious and outrageous posts pertaining to his renewed follicles. For his first announcement to social media, he posted this jubilant and priceless video to his Instagram:
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