After the new article featuring Medipost’s hair growth cosmetic was published, Jay Lee PhD of Medipost, began chiming in on the comments section. He first shared that Medipost is currently engaging in a larger clinical trial for the CM3 product which would include higher scale Norwood’s. Then, in a following comment he revealed that Medipost is developing a potentially more advanced hair growth product as well. Here are his words:
No one wants to deal with premature balding, thinning hair, or outright hair loss, but these conditions affect many people, both men and women. If you’re one of those people, understand that you don’t need to deal with the anxiety and embarrassment of losing your hair. There are many hair loss shampoos on the market that have been proven to work—and they can work for you, too.
Dr. Carlos Wesley, a hair restoration surgeon in Manhattan, said that women in his practice respond better to P.R.P. than men do, which may have something to do with the fact that women with genetic hair loss tend to have more inflammatory cells around the follicles. From 2013 to 2014, he said, he had an 83 percent increase in female patients, in part because of P.R.P.
David made this claim back in 2000. But fast-forward a few years and his enhanced compensation strategy begins to look a little quaint. Androgenetic alopecia, or male pattern baldness, afflicts about half of all men aged 50 and they can’t all reinvent the sitcom. And significant advances in the £3bn hair regrowth industry mean that they have other, seemingly easier, options. The man who is “ideally bald” (to use Vladimir Nabokov’s description of his comic hero, Pnin) may soon become a rare sight.
You may not know it, but stress affects your health in a number of different ways. It can zap your energy, make you feel physically ill, and even cause your hair to fall out. That’s right, stress plays a big role in contributing to thinning hair. On its own, stress-related hair loss is usually temporary and grows back over time. However, it can also speed up other forms of hair loss like male pattern baldness.
Things get interesting when we discover a patent which was filed by Sangamo in May 2017 titled “Targeted Treatment of Androgenic Alopecia.” As with virtually all patents, the lengthy text of the patent is difficult to read or to create a concise summary from. An intriguing aspect of this news is Sangamo works in several technology spaces, including previously mentioned genome editing and gene therapy, either would make an advanced type of hair growth therapy we have never seen before. One caveat to mention is the company’s pipeline does not currently display any indication for alopecia, meaning the therapy is not fully developed yet, so it will be some time before trials begin. We certainly hope to hear more from Sangamo Therapeutics as soon as possible about their interesting development for hair growth technology.
If you’re a gentleman who’s been noticing a receding hairline or is worried about balding, the first step is to schedule a visit with a doctor or dermatologist and make sure your hair loss isn’t a sign of a more serious health issue. “Not all hair loss is male-pattern hair loss,” explains Dr. Marc Glashofer, a board-certified dermatologist specializing in hair loss and practicing in northern New Jersey. A thyroid disorder, an autoimmune disease, or even a scalp issue could be making you look like Bruce Willis in Die Hard 2. But most hair loss is androgenetic alopecia, also known as male-pattern baldness, and fortunately (or not, depending on your perspective), it’s just a symptom of getting older.
Many pharmaceutical companies and researchers are in the search for a hair loss cure. This is because 7 out of 10 men and 4 out of 10 women suffer from androgenic alopecia (genetically caused hair loss) in their lifetime. In the United States that amounts to around 80 million men and 40 million women currently suffering from hair loss. Of course, a permanent cure would relieve a huge percentage of the population.
Scientists from the Indiana University School of Medicine have for the first time created skin with hair follicles using mice stem cells. Research was led by Professor Karl Koehler. The team was able to grow both the epidermis and dermis layers of skin to create a realistic skin model. An interesting quote from Professor Koehler: “It looks like a little ball of pocket lint that floats around in the culture medium. The skin develops as a spherical cyst and then the hair follicles grow outward in all directions – like dandelion seeds.”
Finally, if these tests come back normal, your dermatologist may suggest a scalp biopsy of a couple of two-millimeter sections taken from your scalp under local anesthesia ($400 and up). It can determine whether genetic hair loss, telogen effluvium (a condition in which hair falls out from stress or rapid weight gain), or a disease (such as lupus) is the cause of your shedding, and your dermatologist can treat you accordingly.
Quietly, however, progress churns. Joseph is the pseudonymous proprietor of the Web site Follicle Thought, a popular destination for hair-loss obsessives. Follicle Thought is dedicated to “what’s next,” Joseph told me. “What could be coming? Obviously we have other things to cure. But, like, what is the world doing about hair? Hundreds of millions of people really want it. It’s a really deep, emotional, psychological issue for people.” He paused. “I’ve put so much thought into that question.”
“Smelling” Receptor Keeps Hair Growing – Many of you may have noticed the headlines regarding sandalwood and hair growth over the past week. The research everyone is talking about comes from Ralf Paus and his team at the Monasterium Laboratory GmbH. For the record, Paus is also the main researcher behind the WAY-316606 hair growth discovery. This time Paus et al identified an olfactory receptor in hair follicles, OR2AT4, which plays a role in regulating hair growth or inhibition. Olfacory receptors are responsible for detecting odors in cell membranes and provide the basis for our sense of smell, they do carry out additional functions though, as demonstrated by Paus.
Key features: The Thick & full Hair Growth Set by DermaChange is a go-to option for hair loss and thinning strands — it's chock-full of vitamins and oils that promote hair regrowth and prevent hair loss by hydrating, strengthening, and thickening strands with natural ingredients. It's also made with a gentle, sulfate-free formula, so it's a safe choice for color-treated hair and sensitive scalps.
Disruptions in the normal length of each phase, which can cause hair loss and hair thinning, may be the result of a number of internal and external stimuli. These are also what we call the triggers and causes of your hair loss. As a quick example, dieting can leave the body stressed and in need of important nutrients. Because of this stress, hair growth may be cut shorter than usual and there is an early onset of telogen or shedding of hair.
Other options include microneedling ($1,200 and up per treatment) and platelet-replacement therapy (also $1,200 and up per treatment), which are usually offered in conjunction. Your scalp will be numbed first so you don’t feel the pinpricks involved in microneedling. They promote hair regeneration by spurring wound healing, and platelet-replacement therapy involves injecting growth factors into those wounds. “Combination therapy typically works better than monotherapy and usually yields results after three monthly treatments,” says Sadick, and should be teamed with an at-home minoxidil treatment.
“The DHT hormone (dihydrotestosterone) can contribute to thinning in women who are genetically predisposed to female pattern thinning,” Fusco says. For those whose case falls into this category, she advises a prescription shampoo with ketoconazole 2 percent, as it has anti-androgenic properties. “Ketoconazole has been proposed to disrupt the pathway of DHT leading to thinning of follicles.”
“I was 21 when I noticed my hair getting thinner,” says David Anderson, 45, who has had seven hair transplants. He is now senior patient adviser at the Maitland Clinic in Liverpool, one of the country’s leading hair transplant clinics, where he raises awareness of the vulnerability of sufferers. “It was devastating. It completely consumed my existence. Now, I really regret that. But time and again, I’m meeting patients going through the same anxieties. It’s an epidemic. A lot of people don’t understand how it can make you feel.”
The average person loses 50 to 100 hairs per day naturally due to this cycle. But if the process is interrupted at any stage—for example, if the follicle doesn’t come back out of resting mode or starts to shrink—hair loss and hair thinning can result. Interruptions to the cycle can be caused by hormones, stress, poor diet, chemical hair treatments, certain medications, and, of course, good ol' genetics.
Post surgery care is important if you've undergone a hair transplant or surgery. Expect some swelling of the face and on the scalp a couple of days after the procedure. To fast track hair growth, you may be asked to use Minoxidil or Finasteride. Saline is applied on the grafts for a few days, while you will be prescribed to use a diluted shampoo that is softer and less harsh on the scalp. Hair growth in the transplanted areas becomes visible in three - six months.
2. Volumizing shampoos and treatments. Typically, these work by depositing ingredients, like wheat protein and keratin, that adhere to the hair shaft to a) thicken it and b) create spaces between hairs so you look like you have more of it. Try Kiehl’s Rice & Wheat Volumizing Shampoo ($18) with hydrolyzed wheat protein; Rogers likes Redken Cerafill Defy Shampoo and Conditioner ($20 each) with ceramides that bulk up hair.
It is called the vampire treatment because blood is taken from the patient that removes the platelet rich plasma. Then, the PRP is injected back into the scalp. This energizes the scalp with new active blood flow. Treatment is available at select clinics but widespread adoption may become the norm. It is less invasive than hair transplants but costs more if you count the cost of doing many sessions.