And, for all of these collective efforts, Christiano reminded me, the only things that have really worked were discovered accidentally. Soon to join minoxidil and finasteride will be Xeljanz, or tofacitinib: originally developed for rheumatoid arthritis, it has remarkable effects on hair growth for patients with alopecia areata, an autoimmune disorder that causes patients to lose hair in big patches over their entire bodies.
Dr. Zeichner recommends choosing a shampoo and conditioner that matches the issue you're experiencing. If you have thinning or shedding hair, he says to opt for strengthening products made with keratin or to choose one infused with vitamins and antioxidants, as these can all strengthen strands and create a better environment for your hair follicles to function.
This video is equally hilarious. Once again, there is inspiration here. Deion had a 5,000+ FUE last year and received good results from it. But he’s not done yet, he has the resources to have another procedure and get as close as he can to the result that he really wants, so he did. Surely, he’s just about maxing-out his donor area now. Once again, congratulations to Deion for pursuing his hair growth goals. Enjoy the video and have a big laugh. OOOOeeee.
Head over to the main Articles page to read an update from head researcher Junji Fukuda PhD of Yokohama National University. This is the research that spurred the “french fry hair cure” craze of recent news headlines. I asked Junji in a Q&A if he has received any interest from bigger companies to commercialize his technology. Find his answer and more insight to what lead him to hair follicle research in the full article.
This moisturizing double-duty product is incredibly well rated (and you don’t even have to pay the pink tax to boot). Soy proteins and shea butter add silky strength, while scalp-tingling peppermint and rosemary provide minty freshness and lift at the root. “The thickening properties of the shampoo are great at this price point, so if you have thin or thinning hair, this will add some volume,” wrote one reviewer. “I also noticed that this is the first shampoo/conditioner shampoo that tends to actually condition your hair."
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“No probs. If you come across any other documentaries in the UK that you cannot view in the States feel free to ask me to watch it and feedback. I think sites like yours give people an incentive to keep looking forward with some optimism. Without doubt a feasible hair loss solution isn’t far away. I think it will most likely be a next gen hair transplant through hair cloning. But what ever it might be, as you said in a previous comment there have never been as many players in the hair loss industry. There will be a few false starts, but one, quickly followed by others will come through. It’s just the wait 🙁 But you never know with Shiseido, Brotzu and Haircell releasing data this year it could be sooner than we think 🙂 Kind regards” – Welsh Dragon
When you're investing considerable time and money on a mix of hair treatments and cures, the last things you should be doing are those that will only aggravate your condition. Likewise, when your hair has finally grown back, the last thing you would want is for you to go through another horrific episode of hair loss. Preventing further - or another case of hair loss, and stopping it before it actually happens should be your goal.
It never hurts to do a little bit of research when exploring treatment options for hair loss. But at some point, you'll probably want to talk with a physician so that you can get a professional opinion about how to combat hair loss. We don't recommend cutting corners by exploring cheaper homeopathic and all-natural remedies as an alternative. Drugs like finasteride and minoxidil are clinically proven to treat male pattern baldness and even reverse hair loss with a majority of men, and they’re approved by the FDA.
Alopecia areata. This condition, called patchy hair loss, is the opposite of pattern baldness. Whereas in the former, thinning hair follows a pattern, alopecia areata is marked by smooth and bald patches anywhere on the scalp. The bald patches are circular, and can be as small as a pencil eraser or as big as a quarter. It begins with one or two spots that multiply on other parts of the head. The condition is caused by an autoimmune disease where the antibodies mistake the hair as the "enemy" and start attacking it, resulting into hair loss.
Two clinical trials have been ran as a proof of concept for Histogen. Terminal hair count and hair thickness noticeably increased after just 12 weeks. Due to this success, Histogen plans to conduct a Phase 1 Clinical Study in the United States. This will be an injectable which when injected into the scalp will stimulate dormant hair follicles and induce new hair follicle formation (think Botox but for hair follicles instead of skin cells). HSC660 is an ongoing female hair loss trial that will run for 22 weeks and a late stage (Phase 3 trial) for men has initiated in Mexico. Histogen founder Gail Naughton even went so far to reveal commercialization, “We’e in very late-stage negotiations with some huge retail partners,” she says. It may not be a magic bullet, but it would sure be nice to have an alternative/supplement to Rogaine that actually stimulates growth.
Hair growth is a giant industry, with estimated annual sales of $3.6 billion. And every one of those dollars goes to products that do not provide actual hair regeneration. Rogaine and Propecia, the market leaders, can slow hair loss, but they don’t grow new hair. They also come with the small risk of serious side effects. In 2011, Men’s Health reported on a Propecia user who “lost all pleasurable sensations in his penis.”

In our research and our conversations with experts, one name kept popping up repeatedly: Rogaine. As the first topical brand FDA-approved to help regrow hair (all the way back in 1988), Rogaine benefits from more than 20 years of clinical trials and consumer feedback. Rogaine was the first brand to offer a 5 percent minoxidil foam solution when it debuted Men’s Rogaine Unscented Foam in 2006, and virtually every treatment developed since (for both men and women) has been an imitation or derivation of that formula. 

Many pharmaceutical companies and researchers are in the search for a hair loss cure. This is because 7 out of 10 men and 4 out of 10 women suffer from androgenic alopecia (genetically caused hair loss) in their lifetime. In the United States that amounts to around 80 million men and 40 million women currently suffering from hair loss. Of course, a permanent cure would relieve a huge percentage of the population.
Dr. Melissa Piliang, a dermatologist at the Cleveland Clinic, said that Rogaine works better on the top and crown (for reasons not fully understood, the frontal hairline tends to be more resistant to treatment) and ideally should be started as soon as women notice thinning. “Any regrowth you get is a minimal amount,” Dr. Piliang said. “So the more density when you start, the better results you get.”
Late last week, HairClone officially unveiled its crowdfunding campaign with the Euro-based crowdfunding company Capital Cell. HairClone is offering equity based crowdfunding, which means anyone who makes an investment (£500 minimum) owns equity in the HairClone company. Full details on the campaign are listed in the latest HairClone article on the main page of Follicle Thought.
If you think over-the-counter hair loss shampoos are for you or just want to promote growth and strength, Dr. Schwieger recommends formulas with antioxidants such as vitamin E and ginseng, amino acids, and B-vitamins to help rebuild hair and reduce environmental damage. She cautions against those with parabens, sulfates, and fragrances, which can irritate hair and reduce moisture. Ahead, eight vetted hair loss shampoos to try.
Dr. Hawkshaw and his team were lead to test WAY-316606 for hair growth after studying the effects of cyclosporine A (CsA) on hair growth. They found that CsA reduced the expression of SFRP1 in human hair follicles. After looking for other drug candidates that had a similar effect on SFRP1, WAY-316606 was identified. The team has already tested WAY-316606 on isolated human hair follicles which were donated from hair transplant surgeries, and plans to test the drug in human clinical trials in the future. A timeline for a human clinical trial has not been set yet, Follicle Thought will update this as news is presented.
2. Oil-rich conditioner. “Oils improve hair’s tensile strength,” says Paradi Mirmirani, a hair-loss specialist and dermatologist in Vallejo, California. In other words, oils make hair less likely to break under pressure, which is especially important for thinning hair that’s prone to snapping when brushed or styled. Mirmirani recommends using a conditioner fortified with natural oils, like Burt’s Bees Very Volumizing Pomegranate Conditioner, which contains avocado oil ($8), or Honest Company Conditioner with coconut oil ($10). That one’s got an added benefit: “Coconut oil has been shown to penetrate hair,” says cosmetic chemist Randy Schueller, so it makes your hair stronger from the inside out. (Just don’t load up on pure coconut oil. “You might overshampoo your hair to get it out, and then you’ll end up drying your hair and undoing any benefit,” says Fusco.)

Argan oil is derived from the kernels of the argan tree that is endemic to Morocco. In that country, argan oil has been used for skin and hair problems for centuries.  In the western world, argan oil is now becoming very popular in cosmetic applications. Art Naturals organic argan oil shampoo also includes a huge list of botanical and herbal products, along with essential oils that will improve the texture of your hair significantly.
Know the different types of wigs. Synthetic wigs are easy to style and are less expensive than human hair wigs. On the other hand, wigs made from human hair have a more natural look and feel, and are more preferred by those with permanent cases of hair loss. Though they take longer to style, human hair wigs are worth an investment if you plan on wearing it for a relatively long period of time.
The researchers from the University of Manchester’s Centre for Dermatology Research uncovered this finding through lab tests. They used samples containing scalp hair follicles from more than 40 male hair-transplant patients. The hair follicles were placed in a medium and treated with the drug. Researchers said that those hair follicles were able to grow again because it suppressed the actions of SFRP1.

The Rogaine rep we spoke to explained that the different packaging (and therefore different prices) has to do with the FDA-approval process: “We discovered in clinical trials that the hair loss patterns between men and women are different,” she said by way of explanation. “Men typically have that bald spot on the crown of their head, where women generally have a general thinning throughout, but concentrated more on the top of the head. So for FDA approval, we had to come up with two different, gender-specific products, so the directions were more explanatory.”


A more temporary form of hair loss is telogen effluvium or when hair follicles get stuck in the telogen or resting phase and stop growing new hair. Telogen effluvium can occur three months after a significant medical event like childbirth, surgery, or a high fever, but can also be caused by a thyroid imbalance or iron deficiency. Certain medications like blood thinners and birth control pills are also linked to this form of hair loss.
A clinician diagnoses female pattern hair loss by taking a medical history and examining the scalp. She or he will observe the pattern of hair loss, check for signs of inflammation or infection, and possibly order blood tests to investigate other possible causes of hair loss, including hyperthyroidism, hypothyroidism, and iron deficiency. Unless there are signs of excess androgen activity (such as menstrual irregularities, acne, and unwanted hair growth), a hormonal evaluation is usually unnecessary.
Avacor Physicians Formulation® for Men, Bosley Professional Strength Hair Regrowth Treatment for Men, Follinox-5 Hair Loss Treatment, Kirkland Minoxidil Extra Strength for Men 5% Topical Solution, Leminox for Men, Lipogaine for Men, Lipogaine for Men Sensitive, Men’s Rogaine Extra Strength, Nioxin Minoxidil 5% Hair Regrowth Treatment Extra Strength for Men, Perfect Hair 5% Minoxidil for Men, REDKEN Cerafil Retaliate 5% Hair Regrowth Treatment for Men

Of course, there are plenty of men who wish desperately to restore their youthful locks, and a few — we can think of one powerful one — who cling to elaborate comb-overs, but many balding men simply clip their hair short and go on with their lives. Dermatologists say hair loss is emotionally harder for women, who are often deeply embarrassed by thinning hair even though it's quite common. By the time they reach 50, about 40 percent of women are experiencing what's known as female-pattern hair loss, said Gopal Patel, a dermatologist with Aesthetic Dermatology Associates in Media. Women of African descent struggle with even more conditions that can damage hair follicles and cause bald spots.


After a severe illness, I lost more than half of my formerly beautiful long hair. Since then, I've tried many shampoos claiming to encourage regrowth of healthy hair. Well, I found it! This shampoo really works. It smells great and has resulted in my hair being stronger and shiny; it no longer breaks easily and my hair stays on my head rather than in the hairbrush! Yay! Be sure to follow the instructions for use. A little goes a long way.
Coconut milk / coconut oil. Coconut milk/oil, like aloe vera, is one of the oldest and most common natural ingredients for promoting hair growth and growing healthy, shiny hair. Coconut is rich in protein, iron and other minerals that promote healthy hair and prevent breakage. Apply the coconut milk/oil on your bald spots or all over the scalp, and leave it on overnight. Rinse the next day with cool water. You can do this every time you wash your hair.
In Michael Wolff’s “Fire and Fury,” Kuntzman’s theory is bolstered. Wolff writes that Ivanka Trump “often described the mechanics behind it to friends: an absolutely clean pate—a contained island after scalp-reduction ­surgery—surrounded by a furry circle of hair around the sides and front, from which all ends are drawn up to meet in the center and then swept back and secured by a stiffening spray.”
Unfortunately, as with the aforementioned minoxidil, you’ll begin to lose your hair again if you ever stop taking Finasteride. Additionally, it may cause erectile dysfunction and other sexual problems in men although that’s uncommon. Men who experience these side effects from taking this pill can reverse them; however, that can take up to three months to occur.

Hair transplantation involves harvesting follicles from the back of the head that are DHT resistant and transplanting them to bald areas. A surgeon will remove minuscule plugs of skin that contain a few hairs and implant the plugs where the follicles are inactive. Around 15 percent of hairs emerge from the follicle as a single hair, and 15 percent grow in groups of four or five hairs.


Our specially formulated natural remedy for hair loss and shedding is made with natural ingredients. We use high quality products, such as D Panthenol, tea tree oil and evening primrose, to nourish the scalp. This eliminates current hair loss and prevents future problems. It targets the root of falling hair, and penetrates the scalp and hair follicles for itch free, flake free skin that is nourished and ultra hydrated. Our formula rejuvenates and regenerates skin and hair follicles for revitalized, beautiful hair.
Two clinical trials have been ran as a proof of concept for Histogen. Terminal hair count and hair thickness noticeably increased after just 12 weeks. Due to this success, Histogen plans to conduct a Phase 1 Clinical Study in the United States. This will be an injectable which when injected into the scalp will stimulate dormant hair follicles and induce new hair follicle formation (think Botox but for hair follicles instead of skin cells). HSC660 is an ongoing female hair loss trial that will run for 22 weeks and a late stage (Phase 3 trial) for men has initiated in Mexico. Histogen founder Gail Naughton even went so far to reveal commercialization, “We’e in very late-stage negotiations with some huge retail partners,” she says. It may not be a magic bullet, but it would sure be nice to have an alternative/supplement to Rogaine that actually stimulates growth.
2. Pyrithione zinc shampoo. Traditional volumizing shampoos will give the hair you have a lift so it looks fuller (we like the sulfate-free L’Oréal Paris EverPure Volume Shampoo, $8). But some research suggests shampoos with the antidandruff ingredient zinc pyrithione can mitigate hair loss that’s caused by conditions like dandruff, says Mirmirani. Try Head & Shoulders Deep Moisture Shampoo ($6), and use a conditioner without silicones — they can make hair appear limper, especially if it's applied near the roots (we like Love Beauty and Planet Coconut Water & Mimosa Flower Conditioner, $9).

Other options include microneedling ($1,200 and up per treatment) and platelet-replacement therapy (also $1,200 and up per treatment), which are usually offered in conjunction. Your scalp will be numbed first so you don’t feel the pinpricks involved in microneedling. They promote hair regeneration by spurring wound healing, and platelet-replacement therapy involves injecting growth factors into those wounds. “Combination therapy typically works better than monotherapy and usually yields results after three monthly treatments,” says Sadick, and should be teamed with an at-home minoxidil treatment.
Yet another company has made news this week for phase 2 trial progress. Concert Pharmaceuticals announced today that they have completed enrollment for their phase 2a trial using CTP-543 in alopecia areata. CTP-543 is an oral JAK inhibitor which acts on JAK 1 and 2, it’s also known as ruxolitinib. Concert’s version of ruxolitinib has been modified by the company’s proprietary deuterium chemistry technology which the company hopes will improve its effects on AA.
Follicle Thought is interested in connecting with scientists and startups who are working on hair growth or hair loss prevention research. If you or a colleague is working on hair growth please get in touch on the Contact page, even if you are not ready to share news on the site yet. Follicle Thought can offer networking and other resources to benefit your development. Thanks
Consider other factors besides color. Color is important - your wig or hair piece should match your natural hair to look natural. However, consider also texture. You wig should feel like real hair; it should have a smooth and silky feel. For those that need full coverage, choose a wig that bounces to give the illusion of volume. A wig that has a lacing that fits your natural hair also helps in making sure that you have a more natural looking hairline.

Pura d’or also have a hair loss conditioner compliment to this shampoo but we think it’s a bit overkill to use both(as a bottle of this stuff runs on the pricey side)—but if you love the shampoo the conditioner is also a very popular product that couldn’t hurt. Leave it in for about 3 minutes and let your scalp absorb all those vitamins and minerals.


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See a doctor. While it may be easy to treat hair loss that's caused by stress or other physical or emotional shock, other types, especially those caused by medical conditions, require expert attention. Do not self-medicate. A medical test is necessary to determine the real cause of your hair loss. A medical diagnosis is important in order to rule out other factors that might be the cause of your hair loss. On the surface, it's easy to attribute hair loss to stress or the lack of sleep, but it is highly possible that the hair loss may be caused by an unknown or undetected condition related to hormones or genetics. With the right diagnosis, you'll be able to get the right medication and course of treatment.

Some 30 million women in the United States have hereditary hair loss (compared with 50 million men), according to the American Academy of Dermatology, though that figure does not include the millions more who struggle with thinning hair because of pregnancy, menopause, stress and other health conditions. Barely 5 percent of women are said to be good candidates for hair transplant surgery because women lose hair everywhere, meaning that, unlike with men, there is rarely a luxuriant spot on the back of the head from which to harvest hairs unobtrusively.
These days, when forced into windy outdoor situations, Trump is nearly always seen wearing a Make America Great Again cap. But, one wintry, blustery day this February, Trump walked up the steps of Air Force One capless. In the engrossing video footage, you can see the hair on the back of Trump’s head part and rise, shooting up with power, almost in two separate flaps—one to the left, one to the right.
“There’s the ‘I don’t date bald men’ line – hard to argue with, but still an injury to one’s pride.” Then there are a surprising number of people who call out “baldie!” in the street, or equate a shaved head with homosexuality and/or neo-Nazism. “I’ve had baldist/homophobic abuse in the street a couple of times and I’ve even been asked on the Tube: ‘Are you BNP, mate?’ When I expressed bewilderment at this, I was told: ‘It’s the hair, innit.’”
Like Anderson, he started to lose hair at 21 and tried similarly baroque remedies. “At the time, there was nothing except the snake oil you found at the back of muscle magazines.” He rubbed cayenne pepper into his scalp; he hung upside down; he visited a company that promised a miracle cure that turned out to involve a wig glued on to his head. He looked up a few British trichologists and surmised that trichology was a “study of bullshit” then visited an eminent hair surgeon whose eagerness to perform surgery immediately put him off the idea. It was the discovery of Propecia that ultimately “saved” him. “The drug stopped my hair loss. I had no adverse side effects. I regrew my hair on the crown.”

More good research coming from the University of Alabama at Birmingham shows that a certain gene affecting mitochondrial function can dramatically reverse signs of aging in mice. The aging factors which were shown to be reversible include skin wrinkles, gray hair, and hair loss. Next comes the important phase where the researchers continue forward to translate this discovery to human use. Full article on the front page.
Of course, there are plenty of men who wish desperately to restore their youthful locks, and a few — we can think of one powerful one — who cling to elaborate comb-overs, but many balding men simply clip their hair short and go on with their lives. Dermatologists say hair loss is emotionally harder for women, who are often deeply embarrassed by thinning hair even though it's quite common. By the time they reach 50, about 40 percent of women are experiencing what's known as female-pattern hair loss, said Gopal Patel, a dermatologist with Aesthetic Dermatology Associates in Media. Women of African descent struggle with even more conditions that can damage hair follicles and cause bald spots.
A separate study, published in Skin Therapy Letter — a professional reference site for dermatologists — found that women also benefit from using the more potent 5 percent minoxidil treatment. “Patient-reported improvement in hair volume and coverage appears to be greater with 5 percent minoxidil foam,” reads the report. Plus, because the 5 percent treatment is stronger, women only have to apply it once a day to get the same results as they would with the 2 percent treatment applied twice daily.
1. Hair color. Anytime you dye your hair, you’re increasing the diameter of each strand, which can help add volume when your hair is sparse and fine. As a general rule, ask your colorist to make sure highlights are finer at the top of the head, where hair is the thinnest, and more intense at the bottom, where it’s thickest, says Eva Scrivo, a hairstylist and the owner of the Eva Scrivo Salon in New York City. And beware: A color that contrasts with your scalp (blonde tones if your scalp is dark, deep brunettes if your scalp is light) will make any visible scalp more obvious.
Minoxidil typically comes in 2% and 5% dosage. With the former, hair growth is not visible up until the fourth month (16 weeks) of use, but it could be faster with the 5% dosage.This is most effective especially if you haven't been bald for more than 5 years, your bald patches are less than 10cm across, and most of all, if the bald spots still have some tiny, fine hairs. Studies found that people who have used minoxidil have observed at least minimal to moderate hair growth. The new hair is typically downy soft, but with continued use, it will grow in thickness as the rest of the hair.
Certainly a company with a unique background and game plan, HairClone has received some recent media attention. The UK biotech startup was featured in this month’s publication of “Consulting Room” online magazine. In the article both Dr. Bessam Farjo and Paul Kemp of HairClone provided insight as to the company’s current progress and plans for the future. Things seem to be coming along well for HairClone and we should expect to hear from them again within the next several weeks. Full story is on Articles main page.
There’s also a women’s version (Women’s Rogaine Foam) — but a three-month supply costs $22 more online. The only difference between the two products are the instructions; women are instructed to apply once a day instead of twice. If you’re a woman who doesn’t feel like paying extra for marketing, the men’s product will suffice. A cheaper generic version is Kirkland Signature Minoxidil Foam, but with a longer history on the market and more customer testimonials, Rogaine is our first choice.
If you have flakiness or dryness, Dr. Zeichner notes that it's a good idea to use anti-dandruff shampoos, rather than hydrating products, because they're specifically made to treat inflammation and yeast on the scalp — two underlying causes of dandruff. One ingredient to look for in these options is Zinc Pyrithione. "It's very important to choose the appropriate type of shampoo for your hair type," he says. "The wrong one may not get to the root of your scalp issue."
One hard truth: Hair loss is mostly out of your control. “Baldness comes down to your genes,” says Frederick Joyce, M.D., founder of Rejuvenate! Med Spa and a member of the International Society for Hair Restoration Surgery. “If you have the baldness gene, there are some natural remedies that may make your hair stronger and healthier to slow your hair loss slightly—but they won’t prevent you from going bald. Still, maintaining hair health by eating well and using the right products—combined with medical-grade treatments—can really work all together to help you have a fuller, thicker head of hair.”

You might think, "It's just hair", but think about this: What would you do if you wake up one day without a single strand of hair on your head? However, as we've mentioned, hair loss is a natural physiological process. In the hair growth cycle, old hair has to be shed in order for new hair to grow. As we age, our body's capacity to produce hair also slows down, similar to when our bones stop growing at a certain point in our lives.
Licorice root. Licorice is an herb that is also used to treat and prevent hair loss and hair damage. It soothes the scalp and helps with dry flakes, dandruff and other forms of scalp irritation. Mix a tablespoon of ground licorice root with a cup of milk and a quarter teaspoon of saffron. Apply the paste on the bald patches and leave it on overnight. Rinse in the morning. You can do this two to three times a week.
Minoxidil and oral finasteride are the only treatments currently approved by the U.S. Food and Drug Administration for the treatment of androgenetic alopecia. Both of these drugs stimulate hair regrowth in some men, but are more effective in preventing progression of hair loss. Although there are a number of other treatments listed in various texts, there is not good evidence to support their use.8 

Lipogaine Big 3 does contain ketoconazole, but only a couple other hair loss/thinning related ingredients. Their Big 5 does not contain ketoconazole, but it does contain a proprietary mix of 17 ingredients for hair loss/thinning. It seems to be a more complete shampoo overall, aside from the hair loss aspects. My initial thought is to go with a combination of Big 5 and Nizoral.
Hair spa. A hair spa treatment is one of the most convenient, non-invasive, not to mention, most rejuvenating ways to treat hair loss and promote healthy hair growth. Besides hair loss, it has also been known to address other hair issues like dandruff, split ends, and dry and damaged hair. There are many forms of hair spa treatment depending on what's offered at the salon, but it generally includes an oil massage of the scalp, shampoo and deep conditioning. The whole process helps in blood circulation, bringing the needed nutrients to the follicles, and activates the glands to produce oil.

NTU Working To Prevent Chemo-Induced Loss – Researchers from the National Taiwan University have developed a model for preventing chemotherapy induced hair loss, according to their publication in Cancer Research journal. The team, lead by professor Lin Sung-jan, identified a specific type of cell that hair follicles utilize to compensate for the toxicity which occurs during exposure to ionizing radiation (chemotherapy). These cells are called transit-amplifying cells (TAC). Preclinical animal testing with applied TAC-derived progenitor cells showed a 70-80% reduction in hair loss after chemotherapy and radiotherapy. Importantly, Sung-jan has recently stated he is in talks with companies about conducting trials on humans. It’s interesting to note that Lin Sung-jan has done an extensive amount of research on hair regeneration in the past. Hopefully this treatment could potentially be used for more common types of hair loss as well.


In this simple, step-by-step book, I will reveal how to use a dermaroller to get new hair growth, a natural hair loss cure that helped me re-gain my old hair line, that doesn't involve any fancy drugs like minoxidil. In fact, all you really need in order to achieve the same results like me is a few basic ingredients that you can easily find online.
Short of a full hair transplant, most of us are left to cope daily with the limited benefit of drugs and the profound loss of personal and sexual confidence. Loss of ones hair can push someone into a real state of depression and anxiety, which are real changes to the balance of our chemical biology. So my coping mechanism for my hair loss is to boost my mood with aerobic exercise. Its benefits on clinical depression have been documented and are real. Running lifts my mood and puts me in a feeling of control. It is quite the magic pill and offsets the doom I feel of being out of control over my hair loss. Ask yourself why are there men who feel perfectly confident despite being bald. Maybe they too have found other ways to boost their physical and emotional life with exercise or other modalities. Either way you have to take action and don’t just sit and wait for some drug or lotion to change your life. I am doubtful. Ask yourself if you had your hair back would your sense of inadequacy really change or would it just be short-lived vanity. Take losing your hair as a way to work on you as a person and lift yourself because if not your hair one day you might lose something that cannot grow back or heal. I am moved by seeing disabled people every day live their lives as full as they can and without fear. Do the same. No one cares that we are bald and if they do, they are just vain and petty. Good luck everyone.

For those of you who only check the Updates page, there was a new Brotzu Check-In article published yesterday. Giovanni Brotzu will be presenting data pertaining to his lotion’s use in androgenetic alopecia at an Italian hair research Congress this Saturday, April 14th. We hope to see photo results from the presentation. Check back to the Brotzu article next week for updates.
“Everyone wants to try it,” Altman told me. “We get inundated with e-mails saying, ‘Tell me what the price is, I really don’t care, I’ll buy it.’ ” Weinstein looked at me. “You have your hair,” he said. “I don’t know why you’re interested in this,” Altman chimed in, with wildly unrealistic but much appreciated enthusiasm for my reporting. “ ’Cause eighty million people don’t! There’ll be eighty million people reading this article!”
Aclaris Therapeutics, the company who acquired the rights from Angela Christiano to use JAK inhibitors in alopecia disorders, is currently involved in a wide range of alopecia trials. The company has multiple ongoing trials for alopecia areata, including a trial for eyebrow regrowth, and also a new trial planned for AGA or androgenic alopecia. Full article here.
Jimenez, J. J., Wikramanayake, T. C., Bergfeld, W., Hordinsky, M., Hickman, J. G., Hamblin, M. R., & Schachner, L. A. (2014). Efficacy and Safety of a Low-level Laser Device in the Treatment of Male and Female Pattern Hair Loss: A Multicenter, Randomized, Sham Device-controlled, Double-blind Study. American Journal of Clinical Dermatology, 15(2), 115–127.
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A popular skin care drug—which is intended to target eczema—was just found to have an unusual side effect: hair growth. According to an article on Newsweek, the FDA-approved drug dupilumab was given to a 13-year-old alopecia sufferer to treat her eczema. The patient, who hadn’t grown hair on her scalp since she was two, suddenly grew a significant amount of hair on her head after continual use of the drug, a study in the journal JAMA Dermatology reports.
Due to the concern of several readers, I’ve removed the link to the new Trinov website that has popped up on the net. For now, the website only contains an email address subscription box which really poses no issue to anyone who subscribed. At this time, it’s not confirmed who the actual owner of the new Trinov site is, so use your discretion until we find out more regarding this matter. Until more information is known the website will not be shared on Follicle Thought.
Avacor Physicians Formulation® for Men, Bosley Professional Strength Hair Regrowth Treatment for Men, Follinox-5 Hair Loss Treatment, Kirkland Minoxidil Extra Strength for Men 5% Topical Solution, Leminox for Men, Lipogaine for Men, Lipogaine for Men Sensitive, Men’s Rogaine Extra Strength, Nioxin Minoxidil 5% Hair Regrowth Treatment Extra Strength for Men, Perfect Hair 5% Minoxidil for Men, REDKEN Cerafil Retaliate 5% Hair Regrowth Treatment for Men

Would there be any harm/benefit in combining the use of two hair-loss prevention shampoos, to take advantage of different ingredients and functions? Mainly Nizoral, at the twice a week recommendation, plus the Argan Oil Shampoo twice a week? I have somewhat oily hair and do get dandruff from time to time, but I do feel after washing my hair, it can feel dry and stiff. Just wondering if a combination of the two (one for dandruff, and one for healthy, thicker hair) might prove effective. Also, would you have any recommendations on a combo? Thanks!


With those pinned down, it wasn’t hard to determine which don’t actually work. Pretty much all the “active” ingredients listed in ineffective treatments — from biotin and zinc to emu oil and saw palmetto — have never been proven, and are instead marketed based on logical-seeming correlations. It would make sense that biotin, a B vitamin readily found in hair, skin, and nails, could help hair grow more quickly. And caffeine is a stimulant that works in coffee, so rubbing some on your scalp might wake some of those sleepy follicles… right?
7/26/18 Update: After positive early data, various trials of JAK inhibitors such as Ruxolitinib and Xeljanz are underway. Columbia researchers have had positive results with Xeljanz in 11 out of 12 subjects achieving some regrowth with no adverse side effects over 16 months of treatment. Investigators at Stanford and Yale are conducting three trials of oral and topical tofacitnib and Locks of Love Foundation is fuding another ruxolitinib study. At this time, there are about 15 publications looking at JAK inhibitors and their relationship to alopecia and its variants.
Her hope is that the procedure (she has helped start a company named Rapunzel to develop it) will eventually become another lunchtime cosmetic treatment. Once a patient has had her cells harvested and cultured, they could be stored indefinitely; then, after giving her doctor a month’s notice (the time it takes to grow the million needed), she could pop in for injections. Costs would likely be on par with hair transplants, roughly $10,000 and up.
Approved by the FDA and available in over-the-counter form for both men and women, minoxidil has been found to work in two out of three men. However, and this is a huge problem, if you stop using it, then your hair will actually fall out again and potentially faster than before. Plus, you might not even notice any changes until you’ve been using this medication for at least four months!
Each follicle produces hair for 2 to 6 years and then takes a break for several months. While the hair follicle is in its rest phase, the hair falls out. There are around 100,000 follicles on the scalp, but because each follicle rests at a different time and others produce hairs, hair loss is usually unnoticeable. More noticeable hair loss occurs when there is a disruption to the growth and shedding cycle, or if the hair follicle is obliterated and replaced with scar tissue.
Keranique is another line of products targeted towards women. They offer a complete system consisting of shampoos, conditioners, and topicals. Our testers found that it was one of the harshest shampoos and was not always color safe. Their topical foam contains Minoxidil which can irritate some scalps. Keranique hair products are safe to use and highly effective.  They also have an anti-dandruff shampoo that has received amazing reviews.
Know the different types of wigs. Synthetic wigs are easy to style and are less expensive than human hair wigs. On the other hand, wigs made from human hair have a more natural look and feel, and are more preferred by those with permanent cases of hair loss. Though they take longer to style, human hair wigs are worth an investment if you plan on wearing it for a relatively long period of time.
And just like that, more fascinating hair-related research was published in PLOS Biology. A team of researchers lead by Dr. Nathan Hawkshaw of the University of Manchester have identified the drug ‘WAY-316606’ as a potential candidate for hair regrowth. WAY-316606 is an existing drug used to treat osteoporosis. It’s not clear at this time whether WAY-316606 is approved and on the market, or if it was partially developed to treat the bone disease.
Hey there, I'm Shawn, the founder of Tools of Men! This site was created to help out other guys by teaching them proper grooming habits and the basics of sensible style. We try to make things here a bit of fun while giving you clear info. If you want to get in touch with us, drop us a line on the contact page or via social media. Thanks for checking out the site - and make sure to come back again!
In my opinion this shampoo has a "manly" smell. No flowers or sweet smells which is ok. Maybe it's an herb smell. Its not too overpowering and its a scent that is acceptable to both of us which is nice since my husband and I are both using this shampoo. He is real impressed with it and says his hair feels softer. He also thinks it is getting thicker on the top. I see him every day so I'm not sure I notice it. We have only been using it for a month or two so I don't really think that's enough time to see drastic improvement. I did notice the other day that he needs a hair cut so it may be that his is growing faster. I also noticed that I have little short hair sticking up all over my head so I obviously have new growth! I haven't really noticed a reduction in the amount of hair that I am losing but I am so excited to know that I have new hair coming in. I will be 50 this year and my husband is 51 so I know that our hair loss is a normal aging thing but neither of us like it and have tried several different shampoos looking for something that will stop the hair loss. I guess if we can't stop it we'll settle for new growth! Our first bottle of Biotin Shampoo is almost empty and I have decided to get another bottle instead of moving on to something else. This stuff is definitely worth staying with for a while to see how much the hair growth and reduction will improve.

About one-third of women experience hair loss (alopecia) at some time in their lives; among postmenopausal women, as many as two-thirds suffer hair thinning or bald spots. Hair loss in women often has a greater impact than hair loss does on men w, because it's less socially acceptable for them. Alopecia can severely affect a woman's emotional well-being and quality of life.
For the first twenty years of my life, I took having hair for granted. One day, in college, I woke up and looked in the mirror, and was convinced that my hair was falling out. Not receding—dropping, that minute. Later that day, I told a roommate. He took a beat, and then asked, not without kindness, “Were you on PCP?” That semester, in a creative-writing workshop, I was moved enough to write a long, confused story about a teen-ager with male-pattern baldness who suffers a meltdown and robs the hot-dog counter where he works. By my late twenties, hair loss was something that I thought about all the time. I understood, largely, that my obsession was a specific expression of a more general anxiety. I’ve never been to therapy. There are many things that have led me to consider it. But one of the most distinct, definable, and pressing has been my obsession with hair loss.
Rogaine’s foam squirts out just like hair mousse and is applied with “cool, dry hands.” Applying means working the foam down to the scalp where you want to see thicker growth — for it to work, “it has to get into your scalp,” Dr. Wolfeld explains. “If it sits on your hair, it’s not really as effective.” Once massaged, it dissolves into a watery liquid that leaves a tingly sensation, “but no burning!” one of our balding testers was happy to discover.
The patient, a small, vaguely European man in his late forties, had rings on his fingers and a bloody, rectangular gash on the back of his head. It looked like a chunk of missing carpet. Bernstein pointed at the white opening of exposed scalp, and explained how easy it would be to stitch skin together over the gap. This was a traditional process for follicular-unit transplantation. Then Bernstein led me into a second room, where another patient was seated with his face in a massage-table-like padded hole. A portion of the back of his head was marked off. To his right was a boxy gray machine, roughly four feet by four feet, with a jutting mechanical arm. This was the ARTAS Robotic Hair Transplant.
Since PhytoCayne Revitalizing shampoo is so watery, it’s easy to overpour and waste a good amount of this expensive product. That’s one reason we rank it below Revivogen and Nioxin. The more important reason for the #3 ranking is that this shampoo doesn’t do everything that the other two products do. It’s still effective for most users, however, and worth a try.

For hair transplant clinics, this is the ultimate goal. Bald people would make a mad dash to their clinics to get their new heads of hair. Since the main limitation of hair transplantation surgery is how many hairs can be harvested from the back of the scalp before it appears thin, stem cloning (the growing of dermal papilla cells) will solve that problem in totality. Recent research that has taken place in California has taken a big step toward the cure for hair loss.
The average person loses 50 to 100 hairs per day naturally due to this cycle. But if the process is interrupted at any stage—for example, if the follicle doesn’t come back out of resting mode or starts to shrink—hair loss and hair thinning can result. Interruptions to the cycle can be caused by hormones, stress, poor diet, chemical hair treatments, certain medications, and, of course, good ol' genetics.
Literally jumping right out of the woodwork, the company “HCell” has announced they have been granted an orphan designation from the US FDA for their novel treatment of pediatric alopecia areata. The treatment itself it described as a “topical Injection by regenerating hair through a proprietary blend of commercially procured biologic and autologous tissue.” The company also mentions having a treatment for androgenic alopecia in the works as well. More info to come soon. News release here. 
Drugs normally used for rheumatoid arthritis and bone marrow cancer, they are now being studied for their uses as a hair growth medicine. These are a new class of medicines labeled as JAK inhibitors. In one study, 6 out of 9 patients dramatically went from bald to a full head of hair after taking Ruxolitinib for 5 months. In another study several subjects were able to regrow full heads of hair. Unfortunately, sustained use of such drugs will have severe side effects. Many of these concerns would be side stepped if a topical formula could be developed. Researchers at the Department of Dermatology and Genetics and Development at Columbia University Medical center are now studying other JAK inhibitors in placebo controlled studies.
Would there be any harm/benefit in combining the use of two hair-loss prevention shampoos, to take advantage of different ingredients and functions? Mainly Nizoral, at the twice a week recommendation, plus the Argan Oil Shampoo twice a week? I have somewhat oily hair and do get dandruff from time to time, but I do feel after washing my hair, it can feel dry and stiff. Just wondering if a combination of the two (one for dandruff, and one for healthy, thicker hair) might prove effective. Also, would you have any recommendations on a combo? Thanks!
We have yet another biotech research company working on a next-gen hair growth cosmetic product. Their webpage mentions the use of “stem cell culture solution-derived proteins” for hair growth cosmetic products. An imminent release of the product seems unlikely, however it is nice to know how many companies really do want us to have a new product to improve our lives. Website here.
The follicles on the sides of the scalp are more genetically resistant to DHT, which is why male pattern baldness often results in a “crown” of hair. But its downsides are serious. “With women, finasteride is not an option,” says Dr. Wolfeld. “It’s not FDA-approved for women to take, so we don’t prescribe it.” In fact, due to the drug’s effect on hormone levels, pregnant women are advised to not even touch broken or crushed tablets.

"Despite some of the claims, a shampoo or conditioner won’t be able to stop or slow hair loss, nor help with a receding hairline or thicken hair that’s becoming thinner," says trichologist Anabel Kingsley from The Philip Kingsley Trichology Clinic in London. "At best, a thickening shampoo will make hair temporarily thicker for a short period of time, but they certainly won’t help with hair loss or thinning."
“Once that hair has stopped shedding, it does regrow, at a rate of about a centimeter a month,” said Dr. Senna, who suffered from the condition after each of her pregnancies. She shares photos of herself with patients, to show she can sympathize. In one, her entire frontal hairline clearly is growing back in. “If I’d used a treatment, I would have thought it was a miracle drug,” she said.
Can a vitamin D deficiency cause hair loss? People get vitamin D from a variety of foods and from spending time outdoors in sunlight. Vitamin D is an essential nutrient that plays a role in many body functions, including hair growth. In this article, learn how a vitamin D deficiency is related to hair loss, as well as how it can be treated and prevented. Read now
Category: Alopecia Areata, Alopecia Pipeline, Hair Care Products, Hair Growth Pipeline Tags: Alopecia News, Autoimmune Disease Hair Growth, Carboxytherapy For Alopecia, Cures For Hair Loss, Cures For Hair Loss Coming Soon, Cynata Therapeutics, Deion Sanders Hair, Deion Sanders Hair Transplant Results, Gray Hair Cure, Grey Hair Cure, Hair Growth Cosmetic, Hair Loss Cure, Hair Loss News, Hair Stem Cell Cosmetic, JW Pharma Wnt Hair Growth, Organ Technologies Hair Cloning, PTD-DBM Hair Growth, Sandalore, Switch Biotech Hair Growth, WAY-316606 Hair Growth, Yonsei University Hair Research

Hair loss shampoos are an excellent addition to any hair loss prevention regime. They are also a cost-effective and convenient way to start treating hair loss. Sure, not many of these have long term clinical studies completed on their efficacy. However, some of these shampoos are chock full of botanicals and herbs that do have some clinical data backing them up.


A study led by Dr. Noha Doghaim of Tanta University in Egypt showed that carboxytherapy may be a promising treatment option for both alopecia areata and androgenic alopecia. The study comprised 80 subjects who were treated over the period of three months with either placebo or carboxytherapy.  Both groups found favorable results from the carboxytherapy, however during a follow-up examination the improvements in androgenic alopecia subjects had decreased over time. The researchers noted that continual treatments would be necessary to maintain and bolster the benefits for AGA.

As we wait and anticipate the market release of a new hair treatment there may be times when the waiting gets to us and we feel disappointed, frustrated, and even depressed. This is understandable. However, like many other times in life, a simple change of perspective can lift our mood and positively impact how we feel about a situation. When we look at these companies, are we looking at them as commodities? Are they people who owe you something? Or, are they actually rare groups of folks who are working to bring a gift to your life? How often do you really feel grateful to these companies for the work they are doing?


Ms. Imhof, who lives in Land O’Lakes, Fla., was skeptical. The company’s before and after photos seemed too good to be true. But she went for a consultation and made the cut. (Harklinikken’s products are not available to anyone with autoimmune illnesses like alopecia or baldness from scarring, or anyone who is unlikely to see at least a 30 percent increase in growth.)
The only nonchemical option offered up by the dermatologists I spoke with — short of a surgical hair transplant or platelet-rich plasma therapy, which is like Kim Kardashian’s vampire facial but for your scalp — was the laser comb. First cleared by the FDA in 2009, the HairMax LaserComb is a handheld laser device that is designed to promote hair growth. As the manufacturer explains in a letter to the FDA, “The device provides distributed laser light to the scalp while the comb teeth simultaneously part the user’s hair to ensure the laser light reaches the user’s scalp,” which, in turn, stimulates the hair follicles.

You are eligible for a full refund if no ShippingPass-eligible orders have been placed. You cannot receive a refund if you have placed a ShippingPass-eligible order. In this case, the Customer Care team will remove your account from auto-renewal to ensure you are not charged for an additional year and you can continue to use the subscription until the end of your subscription term.
From the top of my head, I don’t remember if the Lipogaine’s Big 3 Shampoo contains ketoconazole but if it does, then that’s a definite plus. Another thing you can do is buy Nizoral and use it in conjunction with The Big 5 Shampoo. So for example, use Nizoral on Mondays and Thursdays and The Big 5 in all the days in between. That way you’d get all the benefits.
Minoxidil is a similar treatment to finasteride and is also available in the UK as a generic or as the well known brand-name “Regaine”. Minoxidil can be bought over the counter, unlike Propecia or finasteride, and comes in the form of a lotion, foam or cream that is rubbed into the scalp every day. Minoxidil is less effective than finasteride (only 60% of men who used Regaine Extra Strength reported regrowth after 48 weeks) but is still a viable option for men seeking treatment. It is also suitable for use by women, and can be used to treat alopecia areata. However, as with finasteride, any beneficial effects will cease once treatment has stopped.
The Brotzu lotion has been back in Italian headlines over the past week. It’s not clear what has prompted this wave of Brotzu news, but we know there has been significant interest surrounding the lotion since it first spread across the international hair-ternet. Recently, enthusiasts have also gone as far to start an online petition advocating for Fidia Pharma and Brotzu to release the heralded lotion. 
I am so happy with this product. I have thinning hair and have used many products in the past trying to at least stop it. I don't expect a miracle for it to grow back but I would love to just stop the hair falling out. Immediately after using this just one day I already noticed improvements. I was told my hair shined more, it was softer and also fuller. The hair falling out has improved a lot. I have not personally noticed hair growth yet but its only been 2 weeks now and I can say without a doubt it has made my hair healthier. I will be getting more for sure
2. Oil-rich conditioner. “Oils improve hair’s tensile strength,” says Paradi Mirmirani, a hair-loss specialist and dermatologist in Vallejo, California. In other words, oils make hair less likely to break under pressure, which is especially important for thinning hair that’s prone to snapping when brushed or styled. Mirmirani recommends using a conditioner fortified with natural oils, like Burt’s Bees Very Volumizing Pomegranate Conditioner, which contains avocado oil ($8), or Honest Company Conditioner with coconut oil ($10). That one’s got an added benefit: “Coconut oil has been shown to penetrate hair,” says cosmetic chemist Randy Schueller, so it makes your hair stronger from the inside out. (Just don’t load up on pure coconut oil. “You might overshampoo your hair to get it out, and then you’ll end up drying your hair and undoing any benefit,” says Fusco.) 

What is one thing you can do to help new hair growth treatments become a reality? Be creative. Your activity, whatever it might be, will give you a sense of empowerment. You will be contributing to the goal of new hair growth treatments becoming available in the world. How could you feel apathetic or helpless when you are taking the initiative to get involved? Please share in the comments of this page your ideas or practices for how you personally choose to contribute to the success of new hair growth treatments becoming a reality. Remember, every idea or action is worthwhile and supports the outcome. Be authentic and best wishes. Thank you
“There’s people selling pills and creams and lotions and whatever else, and sometimes you can’t even trust what ingredients they have in there,” he warned us when we spoke to him over the phone. Key takeaway: The hair loss industry is crazy dishonest, so we eliminated any treatments (especially homeopathic methods) that aren’t based in concrete, peer-reviewed science.
More good research coming from the University of Alabama at Birmingham shows that a certain gene affecting mitochondrial function can dramatically reverse signs of aging in mice. The aging factors which were shown to be reversible include skin wrinkles, gray hair, and hair loss. Next comes the important phase where the researchers continue forward to translate this discovery to human use. Full article on the front page.
Involutional alopecia. This one is less of a medical condition (it's not caused by a disease or genetics) and is more concerned with the hair growth cycle. Also called telogen effluvium, this condition is marked by a long dormant phase of telogen than growth or anagen. This type of hair loss is the second most common next to pattern baldness but is also the most unpredictable and difficult to pinpoint its cause. Studies have shown that the dormancy phase in the hair growth cycle is related to a range of factors, including hormonal imbalances, pregnancy in women, stress, diet, etc.
A popular skin care drug—which is intended to target eczema—was just found to have an unusual side effect: hair growth. According to an article on Newsweek, the FDA-approved drug dupilumab was given to a 13-year-old alopecia sufferer to treat her eczema. The patient, who hadn’t grown hair on her scalp since she was two, suddenly grew a significant amount of hair on her head after continual use of the drug, a study in the journal JAMA Dermatology reports.
If you're dealing with premature hair loss, you know how frustrating it can be to treat. What can be equally as frustrating is trying to find hair products that will actually help remedy thinning or breaking locks. To help you navigate the confusing world of hair loss, I reached out to Manhattan-based dermatologist Dr. Joshua Zeichner and used his recommendations to find the best shampoo and conditioner for hair loss.

Blow dryers, flat irons, and other devices: Frequent use of a blow dryer tends to damage hair. The high heat from a blow dryer can boil the water in the hair shaft leaving the hair brittle and prone to breakage. Dermatologists recommend that you allow your hair to air dry. Then style your hair when it is dry. Dermatologists also recommend limiting the use of flat irons (these straighten hair by using high heat) and curling irons.


A diet that is poor or lacking in certain nutrients, particularly iron, protein, and vitamin B, which are essential in the production of keratin, can cause a long telogen phase and a very short anagen stage. On the other hand, excess supply of vitamin A in the body, especially those taken through supplements, can prove to be toxic and can cause a range of adverse body effects including loss of appetite, fatigue and consequently, hair loss.
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