If you’re a gentleman who’s been noticing a receding hairline or is worried about balding, the first step is to schedule a visit with a doctor or dermatologist and make sure your hair loss isn’t a sign of a more serious health issue. “Not all hair loss is male-pattern hair loss,” explains Dr. Marc Glashofer, a board-certified dermatologist specializing in hair loss and practicing in northern New Jersey. A thyroid disorder, an autoimmune disease, or even a scalp issue could be making you look like Bruce Willis in Die Hard 2. But most hair loss is androgenetic alopecia, also known as male-pattern baldness, and fortunately (or not, depending on your perspective), it’s just a symptom of getting older.
Hair practices. Our hair is one of the strongest and most elastic parts of our body. One strand of a healthy hair can be twice as strong as a copper wire of similar thickness. However, not all hair types are equal. Unfortunately, hair care practices and styling can lead to scalp damage and unnecessary pressure on the hair follicles, resulting in hair breakage and loss.
Giovanni Mele, a stylist who owns Giovanni and Pileggi in Center City, said many women with thinning hair try to wear their hair long. He thinks they're much better off with short, pixie-like styles with light layering on top. He recommends that lighter-skinned women choose colors that are a little darker than blond or gray. He is a fan of a hair-thickening product made by Nioxin.
Christiano is more of a skeptic. Lab results are nice, she said, but “you can grow mouse or rat hair sixteen ways till Sunday. They grow beautifully!” She laughed. “Humans, not so much.” She points out that there’s so much we still don’t understand. For one: Why does the hair on the back of men’s heads stick around, even when all the rest drops? She also counsels caution when playing God with hair loss. Some companies are seeking hair-restoration cures by attempting to modify developmental-cell pathways. Those pathways, Christiano says, “are potent, and so it’s tempting, but you have to make sure it’s well enough controlled that you don’t initiate a cancer signal.”
Would there be any harm/benefit in combining the use of two hair-loss prevention shampoos, to take advantage of different ingredients and functions? Mainly Nizoral, at the twice a week recommendation, plus the Argan Oil Shampoo twice a week? I have somewhat oily hair and do get dandruff from time to time, but I do feel after washing my hair, it can feel dry and stiff. Just wondering if a combination of the two (one for dandruff, and one for healthy, thicker hair) might prove effective. Also, would you have any recommendations on a combo? Thanks!
If you do decide to start treatment to save your hair, a good place to start is with minoxidil, more commonly known as Rogaine. Don’t expect this hair-loss treatment to create luscious locks; minoxidil is better at slowing down or preventing more loss rather than promoting hair growth. But, according to Dr. Amy McMichael, professor and chair of Wake Forest Baptist Medical Center’s Department of Dermatology, it is effective “if used as recommended, with evidence of improvement seen around six to nine months.” Simply massage the foam or solution into your scalp once or twice daily, and for best results, use a formula with 5 percent concentration.
Along with male pattern baldness, there is also a condition known as female pattern baldness, in which hair thins on the top of the head. Less is known about this type of hair loss, but it is more common in women who have been through the menopause. Female pattern baldness cannot be treated with finasteride (as with male pattern baldness), but it can be treated with minoxidil. Minoxidil is rubbed into the scalp once or twice a day and should start to show results after about four months. After ceasing treatment with minoxidil, hair loss should resume within a few months.
Disruptions in the normal length of each phase, which can cause hair loss and hair thinning, may be the result of a number of internal and external stimuli. These are also what we call the triggers and causes of your hair loss. As a quick example, dieting can leave the body stressed and in need of important nutrients. Because of this stress, hair growth may be cut shorter than usual and there is an early onset of telogen or shedding of hair.
One of the downsides to the product is that you pay hand over foot for all those special ingredients DS packed into this bottle. It’s not the cheap crap that most manufacturers throw into your standard shampoos. It is expensive stuff, and using it daily means there’s no real way of making it last a long time either. The bottom line is you have to bite the bullet but with all the ingredients in this bottle, you’re getting your money’s worth.
Weinstein has big dark eyebrows and a kind face. Kind of an Elliott Gould vibe. I looked at his head. There was a spotty, thatchy outcropping of gray-black hair. Not exactly an overflowing abundance, but hair, to be sure. “I had nothing on top,” Weinstein said. “You can see—I grew my hair back! And it grew back more or less the color I had when I was young.”
Examination of the scalp in patients with telogen effluvium typically shows uniform hair thinning. The presence of erythema, scaling, or inflammation; altered or uneven hair distribution; or changes in shaft caliber, length, shape, or fragility may suggest other diagnoses. Laboratory investigations are indicated if the history and physical examination findings suggest underlying systemic disorders (e.g., iron deficiency anemia, zinc deficiency, renal or liver disease, thyroid disease).
A diet that is poor or lacking in certain nutrients, particularly iron, protein, and vitamin B, which are essential in the production of keratin, can cause a long telogen phase and a very short anagen stage. On the other hand, excess supply of vitamin A in the body, especially those taken through supplements, can prove to be toxic and can cause a range of adverse body effects including loss of appetite, fatigue and consequently, hair loss.
Lund, Sweden, March 7, 2018: Follicum AB (“Follicum” or “the company”) today announced that the first patient has been treated in the Phase IIa clinical trial in Germany with its lead candidate FOL-005 on 60 patients with hair loss. The study is conducted at Clinical Research Center for Hair and Skin Science (“CRC”) in Berlin and bioskin, Hamburg, Germany. The global market for pharmaceutical hair loss products for both men and women is estimated to be worth $3 billion. The available drug products have unwanted side-effects that limit their use.
There are a lot of reasons why your hair may be falling out. It could be hereditary (which you unfortunately can't control), or linked to health- or diet-related changes. Or it could be as simple as the fact that your scalp is stressed by excess buildup—oil, dandruff, multiple days' worth of dry shampoo—that's preventing new hair from growing. Or your strands are (literally) at the breaking point after daily sessions with the flat iron.
Follicum announced yesterday it has successfully completed the development of a topical formulation for FOL-005. The company had been working in parallel to develop an optimal topical version of FOL-005 while an injectable version of the peptide was being used in a clinical trial. Now that the topical formula is completed it will be trialed in a further phase 2 clinical trial which will likely begin very late 2018 or early 2019.
The third and fourth stages are known as telogen and exogen, respectively. In telogen, the hair is supposed to be at "rest" until it finally detaches itself from the follicle and enters the exogen or shedding stage. Once the hair is detached from the follicle, the follicle remains inactive for about three months, after which a new cycle begins again.
"The majority of men lose their hair not through stress, or bad diet, or lack of sleep, but through the genetic trait of male pattern baldness which is hard to treat through shampoos or supplements alone. Women lose their hair for very different reasons, but the argument still stands that a lot of the hair loss products on the market are just offering false hope. That said, there are a few that really work."
The researchers from the University of Manchester’s Centre for Dermatology Research uncovered this finding through lab tests. They used samples containing scalp hair follicles from more than 40 male hair-transplant patients. The hair follicles were placed in a medium and treated with the drug. Researchers said that those hair follicles were able to grow again because it suppressed the actions of SFRP1.
To us, that meant any product with zero proven ingredients, case studies, or FDA clearance — which shrunk our list by a whopping 180 contenders. That’s right, there are only three treatments that have actually been cleared by the FDA and supported with clinical studies: finasteride (commonly marketed as Propecia), minoxidil, and laser treatments. And, since finasteride is prescription-only, it left us with two.
Lately I’ve been receiving a few inquiries from readers about Shiseido and Brotzu release dates. So, I’m going to address the situation here and hope that this will be sufficient until more news comes from direct sources. I estimate that these companies would publicly address the release date of their products by the end of Q3 this year (end of Sept). As consumers we know there’s no guarantees for releases and if one or both of these products reached the market this year it would be a very fortunate situation. So, keep an eye out, but loosen the grip a little. The news will come when it comes. When there is news it will be visible here.
Though, it is important to point out that a lot of these companies are developing procedures that involve implanting hair, which means there is a chance they will be expensive — as we mentioned before, traditional hair transplants are costly. But a few companies and products such as Follicum’s FOL-S-005 and Fidia Pharma’s Brotzu Lotion are being designed as topical treatments.