I noticed significant thinning, and hair all over the sink every morning, from breakage; I use a flat iron sometimes, and my hair is color-treated. I have since started using coconut oil to help manage my frizzy damaged naturally curly hair. It acts as a wonderful styling product, it lends shine and manageability, has also stopped the breakage, you just have to be very careful with the amount that you use. I also use castor oil and rosemary essential oil on my scalp at night and wash in the morning….egg is supposed to be useful for its proteins (must rinse after 20 min with cool water!!) And mayonnaise too, but I haven’t tried that. Best of luck, Friend….
Traction alopecia. Unlike the other two that are caused by genetic or natural factors, this condition is self-caused and occurs most in women. Hair loss happens because of the continuous and constant pulling on the hair that puts pressure on the follicles. Pressure on the hair, brought about by wearing tight hair styles, braiding, weaving, or even hair treatments like bleaching, causes the follicles to loosen their grip on the shaft and eventually cause hair to fall out, leaving bald spots on the scalp or very thin hair strands.
Drugs normally used for rheumatoid arthritis and bone marrow cancer, they are now being studied for their uses as a hair growth medicine. These are a new class of medicines labeled as JAK inhibitors. In one study, 6 out of 9 patients dramatically went from bald to a full head of hair after taking Ruxolitinib for 5 months. In another study several subjects were able to regrow full heads of hair. Unfortunately, sustained use of such drugs will have severe side effects. Many of these concerns would be side stepped if a topical formula could be developed. Researchers at the Department of Dermatology and Genetics and Development at Columbia University Medical center are now studying other JAK inhibitors in placebo controlled studies.

Hair transplantation involves harvesting follicles from the back of the head that are DHT resistant and transplanting them to bald areas. A surgeon will remove minuscule plugs of skin that contain a few hairs and implant the plugs where the follicles are inactive. Around 15 percent of hairs emerge from the follicle as a single hair, and 15 percent grow in groups of four or five hairs.


Since PhytoCayne Revitalizing shampoo is so watery, it’s easy to overpour and waste a good amount of this expensive product. That’s one reason we rank it below Revivogen and Nioxin. The more important reason for the #3 ranking is that this shampoo doesn’t do everything that the other two products do. It’s still effective for most users, however, and worth a try.
The general medical consensus around laser treatments — caps and combs alike — is that low-level laser light therapy stimulates the cells within the hair follicle. These devices may also increase cell metabolism to promote thicker and more durable hair shafts, something that neither minoxidil or finasteride can do. To use the HairMax Ultima, all you have to do is glide the device over your scalp slowly. Treatments should take about eight minutes, and you should do it three days per week for the best results.
Natural hair that is subjected to constant physical trauma from excessive brushing or combing, tight braids or ponytails, or extreme scratching or massage can cause hair at the temples to become weak and to stop growing to its normal length. Clean shaving, especially for men, can cause white bumps to appear on the area where the hair was shaved short, and at times can become infected with pus and leave permanent scarring, affecting hair growth.
Please help. My hair has always been my pride and joy. I figured since it is pretty damn healthy, it could deal with some bleach damage. And I figured the master stylist who did all the color-corrections would know how much would be too much. I was wrong, and now I want to burst into tears every time I look at my hair or touch it. I just don’t know what to do. my hair has also NEVER been shorter than this and it breaks and falls out. What should i do to regrow hair?
Examination of the scalp in patients with telogen effluvium typically shows uniform hair thinning. The presence of erythema, scaling, or inflammation; altered or uneven hair distribution; or changes in shaft caliber, length, shape, or fragility may suggest other diagnoses. Laboratory investigations are indicated if the history and physical examination findings suggest underlying systemic disorders (e.g., iron deficiency anemia, zinc deficiency, renal or liver disease, thyroid disease).
NIZORAL???? What? Are u joking 🙃? NIZORAL make you loose hair , NIZORAL is not á shampoo is a synthetic imidazole antifungal drug used primarily to treat fungal infections. Ketoconazole is sold commercially as a tablet for oral administration (although this use has been discontinued in a number of countries), and in a variety of formulations for topical administration, such as creams (used to treat tinea; cutaneous candidiasis, including candidal paronychia; and pityriasis versicolor) and shampoos (used primarily to treat dandruff—seborrhoeic dermatitis of the scalp).
Due to the concern of several readers, I’ve removed the link to the new Trinov website that has popped up on the net. For now, the website only contains an email address subscription box which really poses no issue to anyone who subscribed. At this time, it’s not confirmed who the actual owner of the new Trinov site is, so use your discretion until we find out more regarding this matter. Until more information is known the website will not be shared on Follicle Thought. 

Researchers from the NIH and the University of Alabama, Birmingham have discovered a connection between the body’s innate immune regulation and hair graying. It was found that the transcritpion factor known as MITF, which plays an important role in melanocyte function, also plays a major role in hair graying. When the body’s immune system is dealing with a pathogenic infection such as bacteria or virus, molecules called interferons will send out signals to the body to take action against the pathogen. If MITF loses control of interferon response in melanocyte stem cells (due to an immune system response), hair turns gray. Essentially, immune system response may contribute to the process of hair graying according to the study.


Tissue expansion. In this procedure, a material called a tissue expander is inserted under portions of the scalp with hair. Saline water is injected for six to eight weeks in order to expand or stretch this portion of hair-bearing skin. The bags are eventually removed and the expanded hair-bearing skin is cut away and moved to the adjacent bald area. This is typically used to address hair loss as a result of burns or injuries on the scalp.
According to practitioners of traditional Chinese medicine, hair health is tied to two things: kidney energy and the blood, which nourish the hair. The solution: acupuncture and Chinese herbs. While there isn't a lot of hard science to back this up, Maureen Conant, a TCM practitioner at Full Bloom Acupuncture in Seattle, says that she's seen women's hair stop falling out and then gradually regenerate after a few months of weekly treatments.
Hair loss is something that affects a huge proportion of men, and yet unfortunately there is no cure. Though you may have heard of certain medicines such as Propecia (finasteride) or Regaine (minoxidil), it is far more accurate to think of these medicines as effective long-term treatments. There are interesting experimental options being trialled currently, yet these established treatments can be effective at preventing hair loss in up to 90% of men.
Each follicle produces hair for 2 to 6 years and then takes a break for several months. While the hair follicle is in its rest phase, the hair falls out. There are around 100,000 follicles on the scalp, but because each follicle rests at a different time and others produce hairs, hair loss is usually unnoticeable. More noticeable hair loss occurs when there is a disruption to the growth and shedding cycle, or if the hair follicle is obliterated and replaced with scar tissue.

“Everyone wants to try it,” Altman told me. “We get inundated with e-mails saying, ‘Tell me what the price is, I really don’t care, I’ll buy it.’ ” Weinstein looked at me. “You have your hair,” he said. “I don’t know why you’re interested in this,” Altman chimed in, with wildly unrealistic but much appreciated enthusiasm for my reporting. “ ’Cause eighty million people don’t! There’ll be eighty million people reading this article!”


Patients with hair loss will often consult their family physician first. Hair loss is not life threatening, but it is distressing and significantly affects the patient's quality of life. The pattern of hair loss may be obvious, such as the bald patches that occur in alopecia areata, or more subtle, such as the diffuse hair loss that occurs in telogen effluvium. As with most conditions, the physician should begin the evaluation with a detailed history and physical examination. It is helpful to determine whether the hair loss is nonscarring (also called noncicatricial), which is reversible, or scarring (also called cicatricial), which is permanent. Scarring alopecia is rare and has various etiologies, including autoimmune diseases such as discoid lupus erythematosus. If the follicular orifices are absent, the alopecia is probably scarring; these patients should be referred to a dermatologist. This article will discuss approaches to nonscarring causes of alopecia.
Hair loss is often distressing and can have a significant effect on the patient's quality of life. Patients may present to their family physician first with diffuse or patchy hair loss. Scarring alopecia is best evaluated by a dermatologist. Nonscarring alopecias can be readily diagnosed and treated in the family physician's office. Androgenetic alopecia can be diagnosed clinically and treated with minoxidil. Alopecia areata is diagnosed by typical patches of hair loss and is self-limited. Tinea capitis causes patches of alopecia that may be erythematous and scaly and must be treated systemically. Telogen effluvium is a nonscarring, noninflammatory alopecia of relatively sudden onset caused by physiologic or emotional stress. Once the precipitating cause is removed, the hair typically will regrow. Trichotillomania is an impulse-control disorder; treatment is aimed at controlling the underlying psychiatric condition. Trichorrhexis nodosa occurs when hairs break secondary to trauma and is often a result of hair styling or overuse of hair products. Anagen effluvium is the abnormal diffuse loss of hair during the growth phase caused by an event that impairs the mitotic activity of the hair follicle, most commonly chemotherapy. Physician support is especially important for patients in this situation.
Finasteride has limitations though, such as the requirement of daily treatment, a limit to how many damaged hair follicles it can revive, and that it may lose its effectiveness overtime for some people. This drug has shown to be better at preventing further hair loss than reversing it (regrowth). Just keep in mind that some side effects might make the hair loss seem more appealing.
During a hair transplant procedure, a dermatologist or cosmetic surgeon removes tiny patches of skin, each containing one to several hairs, from the back or side of your scalp. Sometimes a larger strip of skin containing multiple hair groupings is taken. He or she then implants the hair follicle by follicle into the bald sections. Some doctors recommend using minoxidil after the transplant, to help minimize hair loss. And you may need more than one surgery to get the effect you want. Hereditary hair loss will eventually progress despite surgery.
The Holy Grail remains a drug that will promote regrowth, but this might not be so far away. Earlier this year, Manchester University announced that an osteoporosis drug had been found to have “dramatic results” promoting hair growth when applied to tissue samples in pre-clinical trials. The resultant frenzy left the PhD student responsible, Dr Nathan Hawkshaw, a little dazed. “Every other week, something comes out about hair loss and it doesn’t generate as much media coverage as what I experienced,” he grumbles. He’s in this for the science – there aren’t many fields where you get to mess around with real human tissue – but such is the distress caused by hair loss and such is the potential customer base that interest is always high.
There’s no getting around it – it’s depressing when you first realize that you’re starting to lose your hair. Other signs of natural aging can be hidden or explained away, but thinning or disappearing hair is different. Your hair is not only front-and-center whenever you’re in public, but it’s one of the features which define you through most of your life. To many, hair loss is a traumatic experience which can seem impossible to deal with, let alone overcome.

Yesterday marked the “estimated study completion date” for setipiprant’s phase 2a trial in androgenetic alopecia in males. The participants of the trial received 1000 mg of setipiprant by oral tablets twice a day over a 6 month period. I expect the results to be presented sometime in 2nd half 2018. Here’s to hoping for positive results from this trial and expediency in beginning a phase 2b or phase 3 trial for setipiprant. Clinical trial page here.
"We developed a protocol to drive human pluripotent stem cells to differentiate into dermal papilla cells and confirmed their ability to induce hair growth when transplanted into mice," said Prof. Terskikh. The next step in their research is "to transplant human dermal papilla cells derived from human pluripotent stem cells back into human subjects."
But, there’s an even more important step to take – your participation and contribution. The topic of “a cure for hair loss” or “a hair growth treatment”, for many of us, is one of the most important issues in our lives. What are you doing to support its success? I realize that question may not have previously crossed the mind for many. It’s here now. For a personal example, I’m not a scientist who creates molecules in a lab, so I decided I would organize the hair growth treatment news and spread awareness. It’s been a gratifying practice for me. 
For those of you who only check the Updates page, there was a new Brotzu Check-In article published yesterday. Giovanni Brotzu will be presenting data pertaining to his lotion’s use in androgenetic alopecia at an Italian hair research Congress this Saturday, April 14th. We hope to see photo results from the presentation. Check back to the Brotzu article next week for updates.
Rub the gel-like sap/juice of the aloe vera leaf directly on your scalp. Leave it on for a few hours and then rinse with lukewarm water. Do this three to four times a week. You can also mix a tablespoon of aloe vera gel with wheat grass juice to boost hair growth. Wheatgrass is also rich in protein, vitamins C and E and other minerals. Drink the wheatgrass juice mixed with aloe vera extract for two weeks to stop hair breakage and minimize hair fall.
Hey Frederique, I removed it because it was no longer available for some reason. I’m not sure how well can these shampoos work if you are going through chemo. How you consulted your doctor about it? Ask if minoxidil is safe for your situation. It may be the best solution for your case since your cause for hair loss is not due to DHT. But please don’t take my word for it, consult with a doctor first.
Products like these come from huge pharma companies and are the direct beneficiaries of tens and even hundreds of millions of dollars worth of research and development, compliance, production and advertising. Since drugs have the capacity to significantly change your bodily functions and can cause threatening and undesirable side effects, there’s a need for the government to protect consumers via tough regulations.
While you are waiting for the Big breakthrough, You may want to give Rosemary and Lavender essential oil a shot. I have found that my scalp feels much healthier after using this treatment once a week. I’m in hopes it is stimulating new hair growth as well. Check out some recipes online and reply with your thoughts or other techniques you find helpful. Let’s help each other fight the good fight against hair loss!
The method for applying hair loss shampoo is the same as regular shampoo, i.e., you apply it to wet hair, massage it into the scalp and rinse it. The difference with hair-loss shampoos, however, is that you should leave them in for a longer time before rinsing. Doing so ensures that their ingredients reach your hair’s roots and scalp, where they have the biggest impact.
Dr. Carlos Wesley, a hair restoration surgeon in Manhattan, said that women in his practice respond better to P.R.P. than men do, which may have something to do with the fact that women with genetic hair loss tend to have more inflammatory cells around the follicles. From 2013 to 2014, he said, he had an 83 percent increase in female patients, in part because of P.R.P.
Follica is developing a wounding device that when coupled with a hair stimulant like minoxidil, is found to be more effective at triggering new growth. They like to call this wounding process ‘skin disruption’. The idea behind this treatment is that after the skin is wounded, cells migrate to that area to repair. They then must choose between two paths: healing the skin (making epidermis) or making hair. It is there where Follica sees the window of opportunity, where they can encourage the cells to do the latter and regenerate new and more hair.
A study led by Dr. Noha Doghaim of Tanta University in Egypt showed that carboxytherapy may be a promising treatment option for both alopecia areata and androgenic alopecia. The study comprised 80 subjects who were treated over the period of three months with either placebo or carboxytherapy.  Both groups found favorable results from the carboxytherapy, however during a follow-up examination the improvements in androgenic alopecia subjects had decreased over time. The researchers noted that continual treatments would be necessary to maintain and bolster the benefits for AGA.
Thanks so much for the guidance! After further research I have to agree with you 100%. Lipogaine Big 3 does containe ketoconazole, which would eliminate the need for Nizoral, however the shampoo only contains a few hair loss/thinning related ingredients. The Big 5 contains 17 and just seems like a better overall product. That plus Nizoral twice weekly seems pretty solid to me.
It looks like Organ Technologies’ recent announcement of its hair cloning progress has attracted some investment capital. Earlier this week, Organ Technologies issued a press release announcing that they have issued new shares to three new investors in exchange for approximately 590 million yen. That’s a lot of yen. In US dollars this converts to roughly $5.3 million, still a good haul. The press release mentions: 
A few years ago, Dr. David Weinstein started to lose his hair. “I really was pissed off,” he explained to me recently, in the tidy, tiny conference room of a co-working space in Manhattan. “I’m the only male in my family who managed to keep my hair! And I was in my mid-fifties, and all of a sudden it fell out. I thought, This is nuts. I don’t like this. And then I thought, I know a little bit about regenerative medicine.” Weinstein is a neuroscientist specializing in spinal-cord injuries and nerve regeneration. Working in his lab, in his spare time, he developed a drug compound he called RT1640.
Thanks so much for the guidance! After further research I have to agree with you 100%. Lipogaine Big 3 does containe ketoconazole, which would eliminate the need for Nizoral, however the shampoo only contains a few hair loss/thinning related ingredients. The Big 5 contains 17 and just seems like a better overall product. That plus Nizoral twice weekly seems pretty solid to me.
"Despite some of the claims, a shampoo or conditioner won’t be able to stop or slow hair loss, nor help with a receding hairline or thicken hair that’s becoming thinner," says trichologist Anabel Kingsley from The Philip Kingsley Trichology Clinic in London. "At best, a thickening shampoo will make hair temporarily thicker for a short period of time, but they certainly won’t help with hair loss or thinning."
Along with male pattern baldness, there is also a condition known as female pattern baldness, in which hair thins on the top of the head. Less is known about this type of hair loss, but it is more common in women who have been through the menopause. Female pattern baldness cannot be treated with finasteride (as with male pattern baldness), but it can be treated with minoxidil. Minoxidil is rubbed into the scalp once or twice a day and should start to show results after about four months. After ceasing treatment with minoxidil, hair loss should resume within a few months.
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