The patient, a small, vaguely European man in his late forties, had rings on his fingers and a bloody, rectangular gash on the back of his head. It looked like a chunk of missing carpet. Bernstein pointed at the white opening of exposed scalp, and explained how easy it would be to stitch skin together over the gap. This was a traditional process for follicular-unit transplantation. Then Bernstein led me into a second room, where another patient was seated with his face in a massage-table-like padded hole. A portion of the back of his head was marked off. To his right was a boxy gray machine, roughly four feet by four feet, with a jutting mechanical arm. This was the ARTAS Robotic Hair Transplant.
HCell Inc. announced this week in a press release the addition of two new members to its Board of Directors. Robert P. Ryan PhD and Marlene Haffner MD PhD comprise the additions to the Board. HCell mentions in the release that the respective additions will be supportive to HCell through their combined experience in orphan drug development and FDA regulatory processes.
Women’s magazine ‘New Beauty’ recently featured several prospective hair growth therapies in a print article. The feature contains several interesting and worthwhile anecdotes. Check the Articles main page to read about Dr. Cotsarelis’ new research on setipiprant for female alopecia, Histogen’s view on the number of injection sessions which may be necessary to get the most out of HSC, and more.
This moisturizing double-duty product is incredibly well rated (and you don’t even have to pay the pink tax to boot). Soy proteins and shea butter add silky strength, while scalp-tingling peppermint and rosemary provide minty freshness and lift at the root. “The thickening properties of the shampoo are great at this price point, so if you have thin or thinning hair, this will add some volume,” wrote one reviewer. “I also noticed that this is the first shampoo/conditioner shampoo that tends to actually condition your hair."
1. Hair color. Anytime you dye your hair, you’re increasing the diameter of each strand, which can help add volume when your hair is sparse and fine. As a general rule, ask your colorist to make sure highlights are finer at the top of the head, where hair is the thinnest, and more intense at the bottom, where it’s thickest, says Eva Scrivo, a hairstylist and the owner of the Eva Scrivo Salon in New York City. And beware: A color that contrasts with your scalp (blonde tones if your scalp is dark, deep brunettes if your scalp is light) will make any visible scalp more obvious.
How to use minoxidil: Be sure that your hair and scalp are dry. Using the dropper or spray pump that's provided with the over-the-counter solution, apply it twice daily to every area where your hair is thinning. Gently massage it into the scalp with your fingers so it can reach the hair follicles. Then air-dry your hair, wash your hands thoroughly, and wash off any solution that has dripped onto your forehead or face. Don't shampoo for at least four hours afterwards.
SM04554, Samumed’s topical for androgenic alopecia, is one of the company’s late stage programs. The other late stage program within Samumed is their drug for osteoarthritis. Phase 3 trials are very costly so the numbers here make sense for Samumed to be pushing forward. This news would indicate we should be hearing about Samumed initiating a phase 3 trial for the commercialization of SM04554 in the near future.
You may not know it, but stress affects your health in a number of different ways. It can zap your energy, make you feel physically ill, and even cause your hair to fall out. That’s right, stress plays a big role in contributing to thinning hair. On its own, stress-related hair loss is usually temporary and grows back over time. However, it can also speed up other forms of hair loss like male pattern baldness.
Blow dryers, flat irons, and other devices: Frequent use of a blow dryer tends to damage hair. The high heat from a blow dryer can boil the water in the hair shaft leaving the hair brittle and prone to breakage. Dermatologists recommend that you allow your hair to air dry. Then style your hair when it is dry. Dermatologists also recommend limiting the use of flat irons (these straighten hair by using high heat) and curling irons.
Egg mask. Eggs are one of the riches sources of protein, which is the building block of keratin, as well as other minerals like zinc, iron, selenium, phosphorous and iodine. Mix an egg white with a tablespoon of olive oil and honey to make a paste. Apply it on your hair and leave on for 20 minutes. Rinse and shampoo using cold water. You can apply this egg mask on your hair once a week.

Retin-A, or topical tretinoin, is sometimes used as a combination therapy with minoxidil for androgenic alopecia. It’s important to use this type of medication under the guidance of your doctor. In some circumstances, tretinoin can actually cause hair loss. Some people who have used it at home report that topical retinol creams, serums, and lotions may make hair loss worse.
Researchers from the NIH and the University of Alabama, Birmingham have discovered a connection between the body’s innate immune regulation and hair graying. It was found that the transcritpion factor known as MITF, which plays an important role in melanocyte function, also plays a major role in hair graying. When the body’s immune system is dealing with a pathogenic infection such as bacteria or virus, molecules called interferons will send out signals to the body to take action against the pathogen. If MITF loses control of interferon response in melanocyte stem cells (due to an immune system response), hair turns gray. Essentially, immune system response may contribute to the process of hair graying according to the study.
Things get interesting when we discover a patent which was filed by Sangamo in May 2017 titled “Targeted Treatment of Androgenic Alopecia.” As with virtually all patents, the lengthy text of the patent is difficult to read or to create a concise summary from. An intriguing aspect of this news is Sangamo works in several technology spaces, including previously mentioned genome editing and gene therapy, either would make an advanced type of hair growth therapy we have never seen before. One caveat to mention is the company’s pipeline does not currently display any indication for alopecia, meaning the therapy is not fully developed yet, so it will be some time before trials begin. We certainly hope to hear more from Sangamo Therapeutics as soon as possible about their interesting development for hair growth technology.

There have been recent discussions on Italian hair forum websites that indicate the Brotzu lotion may very well be moving ahead and preparing for imminent release. After commenter “Ahmed” brought it to my attention, I went back to check the Bellicapelli forum (the site which had the information on the Brotzu presentation at the Sitri Congress in April). I found a response from user “carlitos71” on this page which seems to display the new theories on the Brotzu lotion.
The trick about all of these hair-loss products and treatments is that they’ll stop working as soon as you stop using them. “They have to be ready for a lifetime commitment,” says Rieder. But, just like brushing your teeth, as long you keep on keeping on with the scientifically proven preventative treatments, those hairs on your head should be just fine.
Hair transplant surgery – which works by painstakingly moving grafts of hair (typically two to four follicles at a time) from the back of the head to the temples and crown, the first parts to drop – is becoming mainstream. Wayne Rooney was frank about his 48-hour, £30,000 follicular unit extraction at Harley Street Hair Clinic in 2011, and is widely credited with changing attitudes towards the procedure. Actor James Nesbitt had one as he feared he’d lose out on roles as a bald man. “It was something I struggled with,” he said, “and that was probably the vanity in me.”
I hope you’re having a good Friday. While I am a bit flabbergasted that out of the thousands of people who visit this article every week, still not one person has commented with an idea or practice that they can do to help hair growth treatments succeed, I feel the need to share some upliftment today. It’s coming from the original contributor of Feel Good Friday himself, Deion Sanders. A while back I shared a video of Deion getting his second FUE transplant to thicken his hair. The results are starting to come in and Deion could not be more enchanted by his own hair-restoration miracle. For a guy who was basically NW7 before restoration, the result is impressive. Enjoy his sentiments below.
“Smelling” Receptor Keeps Hair Growing – Many of you may have noticed the headlines regarding sandalwood and hair growth over the past week. The research everyone is talking about comes from Ralf Paus and his team at the Monasterium Laboratory GmbH. For the record, Paus is also the main researcher behind the WAY-316606 hair growth discovery. This time Paus et al identified an olfactory receptor in hair follicles, OR2AT4,  which plays a role in regulating hair growth or inhibition. Olfacory receptors are responsible for detecting odors in cell membranes and provide the basis for our sense of smell, they do carry out additional functions though, as demonstrated by Paus.  

Two clinical trials have been ran as a proof of concept for Histogen. Terminal hair count and hair thickness noticeably increased after just 12 weeks. Due to this success, Histogen plans to conduct a Phase 1 Clinical Study in the United States. This will be an injectable which when injected into the scalp will stimulate dormant hair follicles and induce new hair follicle formation (think Botox but for hair follicles instead of skin cells). HSC660 is an ongoing female hair loss trial that will run for 22 weeks and a late stage (Phase 3 trial) for men has initiated in Mexico. Histogen founder Gail Naughton even went so far to reveal commercialization, “We’e in very late-stage negotiations with some huge retail partners,” she says. It may not be a magic bullet, but it would sure be nice to have an alternative/supplement to Rogaine that actually stimulates growth.
I started combining two of them right away – because they both had different ingredients that I really wanted. I combine the Hair Surge for the caffeine, ketoconazole, and saw palmetto, along with the Regenepure DR for the Emu oil. I use a bit of both every day – and though I haven’t noticed a lot of hair coming back in – I HAVE noticed that a whole lot less is falling out. I used to see lots of hair in the tub or in my hand after drying. Hopefully some baby hairs will start so show themselves soon.
According to practitioners of traditional Chinese medicine, hair health is tied to two things: kidney energy and the blood, which nourish the hair. The solution: acupuncture and Chinese herbs. While there isn't a lot of hard science to back this up, Maureen Conant, a TCM practitioner at Full Bloom Acupuncture in Seattle, says that she's seen women's hair stop falling out and then gradually regenerate after a few months of weekly treatments.
There are pharmaceutical solutions, too. Finasteride (often referred to by its brand name, Propecia) and Minoxidil (aka Regaine/Rogaine) are both available via online prescription in the UK. They stop hair falling out as opposed to making it grow back again, though some report more lustrous locks after three months or so. Donald Trump is the world’s most famous Propecia user. “Never go bald,” he once counselled. “The worst thing a man can do is go bald.” He’s not wrong. The anti-bald dating prejudice that David lamented extends to politics. Only five US presidents have ever been bald. As laughable as Trump’s follicular arrangements are, chances are that if nature had taken its course, a bald Trump wouldn’t have got to the White House. Careful what you wish for.
“No probs. If you come across any other documentaries in the UK that you cannot view in the States feel free to ask me to watch it and feedback. I think sites like yours give people an incentive to keep looking forward with some optimism. Without doubt a feasible hair loss solution isn’t far away. I think it will most likely be a next gen hair transplant through hair cloning. But what ever it might be, as you said in a previous comment there have never been as many players in the hair loss industry. There will be a few false starts, but one, quickly followed by others will come through. It’s just the wait 🙁 But you never know with Shiseido, Brotzu and Haircell releasing data this year it could be sooner than we think 🙂 Kind regards” – Welsh Dragon
Since PhytoCayne Revitalizing shampoo is so watery, it’s easy to overpour and waste a good amount of this expensive product. That’s one reason we rank it below Revivogen and Nioxin. The more important reason for the #3 ranking is that this shampoo doesn’t do everything that the other two products do. It’s still effective for most users, however, and worth a try.
3. Surgical hair replacement. If you opt for hair transplantation (which runs $5,000 and up), your dermatologist or hair-replacement surgeon will remove single hair follicles from the back of the head, near the nape of the neck, where your hair is fullest. Once those follicles are harvested, they are then dissected and reimplanted into an area of the scalp where hair is thinning. The procedure takes anywhere from three to six hours, and newly implanted hair will usually begin to grow on its own 3 to 12 months after the treatment session. Traditionally, hair transplantation required removal of an entire strip of scalp, Sadick says, but this new follicle-by-follicle technique looks more natural when it heals and allows patients to get heads of hair as dense-looking as before they started losing it.
Besides cost considerations, a hair transplant is generally prescribed as a last resort for permanent hair loss problems. It is also not allowed for people under the age of 25, those with a continuing problem of hair loss, as well as those with other health conditions like uncontrolled diabetes, serious heart problems and hypertension. Patients whose hair loss is caused by other factors, such as a skin or scalp disorder or who suffer from a psychological condition that causes them to pull at their hair are not recommended for this procedure. Since the procedure requires taking a sample from the back of the head, those who do not have enough follicles from this section that can be used for transplant are not also eligible. 

For those of you who only check the Updates page, there was a new Brotzu Check-In article published yesterday. Giovanni Brotzu will be presenting data pertaining to his lotion’s use in androgenetic alopecia at an Italian hair research Congress this Saturday, April 14th. We hope to see photo results from the presentation. Check back to the Brotzu article next week for updates.
“While nutritious eating isn’t going to bring your hair back by any means, eating plenty of protein-rich foods and healthy fats can make the hair that you still have look thicker and shinier.” Skimping on the B vitamins in particular can interfere with the formation of hair cells and, therefore, hair growth. The best sources of Bs are protein-packed foods like chicken, fish, eggs, and pork, as well as leafy greens such as spinach. (These foods are also good for melting belly fat, so it’s a win win).
For those of you who only check the Updates page, there was a new Brotzu Check-In article published yesterday. Giovanni Brotzu will be presenting data pertaining to his lotion’s use in androgenetic alopecia at an Italian hair research Congress this Saturday, April 14th. We hope to see photo results from the presentation. Check back to the Brotzu article next week for updates.

Treatment for adults with less than 50% of scalp involvement is intralesional triamcinolone acetonide injected intradermally using a 0.5-inch, 30-gauge needle. Maximal volume is 3 mL per session.11 Treatment may be repeated every four to six weeks until resolution or for a maximum of six months. Local adverse effects include transient atrophy and telangiectasia.
Giovanni Mele, a stylist who owns Giovanni and Pileggi in Center City, said many women with thinning hair try to wear their hair long. He thinks they're much better off with short, pixie-like styles with light layering on top. He recommends that lighter-skinned women choose colors that are a little darker than blond or gray. He is a fan of a hair-thickening product made by Nioxin.
More good research coming from the University of Alabama at Birmingham shows that a certain gene affecting mitochondrial function can dramatically reverse signs of aging in mice. The aging factors which were shown to be reversible include skin wrinkles, gray hair, and hair loss. Next comes the important phase where the researchers continue forward to translate this discovery to human use. Full article on the front page.

While techniques have advanced, the bald are no better served, says Spencer Kobren, who runs Bald Truth, a website and podcast in the lustrous world of the alt-bald media. He has learned to be highly suspicious of anything announcing itself as a cure; indeed, he resolutely fails to get excited about RT1640 or the Manchester findings. “I have been doing this for 20 years,” he tells me from his home in Beverly Hills. “When I wrote my book in 1998, they had just found the hair loss gene. There was talk of hair clones. There was a cell-based solution coming out of Japan. It was like: ‘This is it! We’re going to cure this in five years!’” He’ll believe it when he sees it.

Dr. Carlos Wesley, a hair restoration surgeon in Manhattan, said that women in his practice respond better to P.R.P. than men do, which may have something to do with the fact that women with genetic hair loss tend to have more inflammatory cells around the follicles. From 2013 to 2014, he said, he had an 83 percent increase in female patients, in part because of P.R.P.


These days, when forced into windy outdoor situations, Trump is nearly always seen wearing a Make America Great Again cap. But, one wintry, blustery day this February, Trump walked up the steps of Air Force One capless. In the engrossing video footage, you can see the hair on the back of Trump’s head part and rise, shooting up with power, almost in two separate flaps—one to the left, one to the right.
Some factors that are thought to play a role in female hair loss include high androgen birth control pills, menopause, pregnancy, ovarian cysts, and other factors tied to the actions of hormones. The American Hair Loss Association said it’s important that women who have a history of hair loss in their family to be made aware of the potential effects of birth control pills on normal hair growth.
And just like that, more fascinating hair-related research was published in PLOS Biology. A team of researchers lead by Dr. Nathan Hawkshaw of the University of Manchester have identified the drug ‘WAY-316606’ as a potential candidate for hair regrowth. WAY-316606 is an existing drug used to treat osteoporosis. It’s not clear at this time whether WAY-316606 is approved and on the market, or if it was partially developed to treat the bone disease.
In this section we take a look at current hair loss cures in 2018. Using one or more of the treatments below is your best shot at keeping your hair around. However, if a cure is defined as a permanent fix to an ailment, these are far from that definition. Each of these treatments have their own limitations. Most are seen more as hair loss management treatments, rather than permanent hair loss cures.
A very kind and talented hair blogger from Japan, Fuji Maru Kagurazaka, recently contacted me and suggested that the blogs aimed at promoting hair growth treatments/cures for hair loss should unite their efforts and cooperate. While I acknowledge that the websites who are focused on this material are each unique and have their own (and sometimes differing) perspectives, I do believe that civility and solidarity are certainly desirable qualities for this sector.  Fuji wrote up this nice article about my website, check it out (make sure translate is on if you are not fluent in Japanese). And, I encourage you to read his other articles. Fuji has a sincere and highly detailed approach to hair growth blogging. His personality is highly welcomed and refreshing to the online hair community.
But Buckler said hair growth isn’t the only perk to his company’s discovery. It turns out that use in skin repair and tendon regeneration are also possibilities of the technology. “While we were delving deep into the hair follicle, we discovered another cell population,” he said. The hair follicle is actually a minor organ. There are two different cell groupings. One grows hair fibers. Another grows the tissue that the hair follicle fiber grows in.” And it is within this latter cell grouping that the magical main structural protein found in skin and other connective tissues—collagen—is found.

The third and fourth stages are known as telogen and exogen, respectively. In telogen, the hair is supposed to be at "rest" until it finally detaches itself from the follicle and enters the exogen or shedding stage. Once the hair is detached from the follicle, the follicle remains inactive for about three months, after which a new cycle begins again.
Biotin – Naturally found in many of the rich protein foods you eat including nuts, meats, eggs, etc. Biotin (or simply known as Vitamin B7) has been found in many studies to be linked directly to hair growth. Not only are men using this same vitamin to growth thicker beards, but Biotin is also prevalent in many of the leading natural hair loss shampoos on the market as you will see in just a minute. If you are going all-natural root, this ingredient should most definitely be included in the product you select.
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